User profiles for B. Lazzaro

Brian P. Lazzaro

Liberty Hyde Bailey Professor, Cornell University; pdfs available at Homepage link below
Verified email at cornell.edu
Cited by 12007

Antimicrobial peptides: Application informed by evolution

BP Lazzaro, M Zasloff, J Rolff - Science, 2020 - science.org
… with (A) a zone of inhibition assay and (B) a model of the interaction on the membrane. (A) …
(B) The synergistic interaction between PGLa and Magainin 2. Antiparallel PGLa dimers (red…

Immunity in a variable world

BP Lazzaro, TJ Little - … of the Royal Society B: Biological …, 2009 - royalsocietypublishing.org
Immune function is likely to be a critical determinant of an organism's fitness, yet most
natural animal and plant populations exhibit tremendous genetic variation for immune traits. …

Reproduction–immunity trade-offs in insects

RA Schwenke, BP Lazzaro… - Annual review of …, 2016 - annualreviews.org
Immune defense and reproduction are physiologically and energetically demanding
processes and have been observed to trade off in a diversity of female insects. Increased …

[HTML][HTML] Evolution of genes and genomes on the Drosophila phylogeny

…, E Lander, CH Langley, R Lapoint, BP Lazzaro… - Nature, 2007 - hal.science
Comparative analysis of multiple genomes in a phylogenetic framework dramatically improves
the precision and sensitivity of evolutionary inference, producing more robust results than …

Dynamic evolution of the innate immune system in Drosophila

TB Sackton, BP Lazzaro, TA Schlenke, JD Evans… - Nature …, 2007 - nature.com
The availability of complete genome sequence from 12 Drosophila species presents the
opportunity to examine how natural selection has affected patterns of gene family evolution and …

[BOOK][B] School crisis prevention and intervention: The PREPaRE model

…, CN Conolly, SR Jimerson, RC Pesce, BR Lazzaro - 2016 - scholars.csus.edu
Use this book in your school to. Discover critical components of school safety and crisis
response planning and training. Follow the latest federal guidance to develop comprehensive …

[HTML][HTML] The Discovery, Distribution, and Evolution of Viruses Associated with Drosophila melanogaster

…, EH Bayne, B Longdon, AH Buck, BP Lazzaro… - PLoS …, 2015 - journals.plos.org
Drosophila melanogaster is a valuable invertebrate model for viral infection and antiviral
immunity, and is a focus for studies of insect-virus coevolution. Here we use a metagenomic …

Genetic Basis of Natural Variation in D. melanogaster Antibacterial Immunity

BP Lazzaro, BK Sceurman, AG Clark - Science, 2004 - science.org
… (B) Percentage of the phenotypic variance explained by each site. Percentages shown
are of the observed phenotypic variance attributable to genetic line. Because the statistical …

[HTML][HTML] The evolutionary costs of immunological maintenance and deployment

KA McKean, CP Yourth, BP Lazzaro, AG Clark - BMC evolutionary biology, 2008 - Springer
B. Lazzaro isolated the P. rettgeri strain used in this experiment from the hemolymph of a
wild-caught D. melanogaster collected near State College, Pennsylvania, USA. …

Y chromosomal fertility factors kl-2 and kl-3 of Drosophila melanogaster encode dynein heavy chain polypeptides

AB Carvalho, BP Lazzaro… - Proceedings of the …, 2000 - National Acad Sciences
… 2B strongly suggests that several exons of kl-2 and kl-3 genes are missing from our blast …
2B is caused by weak amino acid sequence conservation). AE002706 filled a small portion …