Context Several practice guidelines recommend that depression be evaluated and treated in
patients with cardiovascular disease, but the potential benefits of this are unclear. Objective …

The first formal qualification of safety biomarkers for regulatory decision making marks a
milestone in the application of biomarkers to drug development. Following submission of drug …

… The roles of cGMP and S-nitrosylation in NO-based signaling (A) and enzymatic protein
denitrosylation mediated by the GSNOR and Trx systems (B). A, NOS synthesizes NO, which …

… (B) Raster plot of the activity of each neuron of population 1 (neurons 1–100), population 2
(neurons 101–200) and population 3 (neurons 201–300). Blue spikes are from the excitatory …

Introduction: There has long been an interest in the effects of diet on mental health, and the
interaction of the two with stress; however, the nature of these relationships is not well …

… (B) Time course of serum ALT levels confirmed liver injury after APAP challenge. Neutrophil
quantification by MPO assay revealed the cooccurrence of maximum liver neutrophil …

… the dopamine concentration [A]: (4)If we assume that the sensor response (ie, the normalized
intensity change) is proportional to the Aθ/θ tot ratio, we find that (5)where the parameter B …

The question may be asked why another Guideline manuscript is needed. The reasons are
fivefold:(1) to outline pros and cons of treatment options;(2) to outline areas where further …

… B) Fold change distribution for 69 acetylation sites from 51 acetylated proteins significantly
and robustly upregulated in the cobB mutant relative to its WT parent. Corresponding protein …

… 1B). To rule out aberrant left coronary anatomy as the etiology of reduced infarct size in the
GSNOR −/− mice, silicone casts were made of the mice hearts that revealed similar coronary …