… b, Southern analysis using an internal probe derived from the Nanog homeodomain. … ,
one of the mutant alleles in the RCNβH-B(t) cells was repaired by homologous recombination (…

Poly-ADP-ribosylation is a post-translational modification catalyzed by PARP enzymes with
roles in transcription and chromatin biology. Here we show that distinct macrodomains, …

… We implemented the cspline interpolation in terms of both csplines and cubic B-splines.
A B-spline interpolation is generally less memory intensive because only one B-spline …

… b, We fit a circle to the localizations and reject localizations outside a ring as background
localizations. c, We rotate the localizations to optimally fit an eight-fold-symmetric template and …

… b, Primary sequence of residues in the U-turn motif. Hydrophobic residues (green) tend to be
… b, The Spt16D domain of the FACT complex pulls down replicative Pol1 from yeast whole-…

… Follicular T H cells (T FH ) are crucial for efficient B cell responses by the formation of
germinal centers in the lymph node. In these germinal centers, T FH stimulate B cell proliferation …

… Each domain contained a central seven-stranded b sheet flanked by two or three a helices
on each side. The individual domains packed tightly together forming an interface of 906 A2. …

At the beginning of mammalian life, the genetic material from each parent meets when the
fertilized egg divides. It was previously thought that a single microtubule spindle is …

Gene tagging with fluorescent proteins is essential for investigations of the dynamic properties
of cellular proteins. CRISPR–Cas9 technology is a powerful tool for inserting fluorescent …

Multicenter phase II trials with Gemtuzumab Ozogamicin (GO/Mylotarg®), consisting of a CD33
antibody linked to the cytotoxic drug calicheamicin, have shown a 30% overall response …