User profiles for B. Raphael

Ben Raphael

Professor of Computer Science, Princeton University
Verified email at princeton.edu
Cited by 59379

[HTML][HTML] Eleven grand challenges in single-cell data science

…, H Yang, A Zelikovsky, AC McHardy, BJ Raphael… - Genome biology, 2020 - Springer
The recent boom in microfluidics and combinatorial indexing strategies, combined with low
sequencing costs, has empowered single-cell sequencing technology. Thousands—or even …

Network propagation: a universal amplifier of genetic associations

L Cowen, T Ideker, BJ Raphael, R Sharan - Nature Reviews Genetics, 2017 - nature.com
b | Example network with initial high scores for two of nine nodes (step 0, nodes A and H;
score shown by colour bar). These scores are allowed to propagate over stepwise iterations 0–…

Mental health in complex emergencies

RF Mollica, BL Cardozo, HJ Osofsky, B Raphael… - The Lancet, 2004 - thelancet.com
Mental health is becoming a central issue for public health complex emergencies. In this
review we present a culturally valid mental health action plan based on scienti.c evidence that …

[HTML][HTML] Mutational landscape and significance across 12 major cancer types

…, MJ Walter, MC Wendl, TJ Ley, RK Wilson, BJ Raphael… - Nature, 2013 - nature.com
The Cancer Genome Atlas (TCGA) has used the latest sequencing and analysis methods to
identify somatic variants across thousands of tumours. Here we present data and analytical …

[HTML][HTML] Prolonged Grief Disorder: Psychometric Validation of Criteria Proposed for DSM-V and ICD-11

…, CM Parkes, M Aslan, K Goodkin, B Raphael… - PLoS …, 2009 - journals.plos.org
Background Bereavement is a universal experience, and its association with excess morbidity
and mortality is well established. Nevertheless, grief becomes a serious health concern …

A formal basis for the heuristic determination of minimum cost paths

PE Hart, NJ Nilsson, B Raphael - IEEE transactions on Systems …, 1968 - ieeexplore.ieee.org
B. Rosen, "The gradient projection method for nonlinear programming, pt. I, linear … B. A
Consistency Assumption When a real problem is modeled by a graph, each node of the graph …

The mutational landscape of lethal castration-resistant prostate cancer

…, N Palanisamy, GA Ryslik, F Vandin, BJ Raphael… - Nature, 2012 - nature.com
Abstract Characterization of the prostate cancer transcriptome and genome has identified
chromosomal rearrangements and copy number gains and losses, including ETS gene family …

[PDF][PDF] Integrated genomic characterization of pancreatic ductal adenocarcinoma

BJ Raphael, RH Hruban, AJ Aguirre, RA Moffitt, JJ Yeh… - Cancer cell, 2017 - cell.com
We performed integrated genomic, transcriptomic, and proteomic profiling of 150 pancreatic
ductal adenocarcinoma (PDAC) specimens, including samples with characteristic low …

[PDF][PDF] Multiplatform analysis of 12 cancer types reveals molecular classification within and across tissues of origin

…, LJ Van't Veer, N Lopez-Bigas, PW Laird, BJ Raphael… - Cell, 2014 - cell.com
Recent genomic analyses of pathologically defined tumor types identify "within-a-tissue"
disease subtypes. However, the extent to which genomic signatures are shared across tissues …

[BOOK][B] The anatomy of bereavement: A handbook for the caring professions

B Raphael - 2003 - taylorfrancis.com
… These images may also be powerful factors in leading to the beginning of the mother-infant
relationship, motivating the conception in some instances (Raphael 1972a). It is likely that very …