User profiles for B. Readhead

Ben Readhead

ASU-Banner, Neurodegenerative Disease Research Center
Verified email at asu.edu
Cited by 5164

In silico methods for drug repurposing and pharmacology

…, BA Kidd, K Shameer, BP Readhead… - … Systems Biology and …, 2016 - Wiley Online Library
… (b) is recreated based on a figure by Wikimedia user ‘Dcirovic.’ Licensed under CC0 via …
called a pharmacophore model (see Figure 5(b)), containing the chemical features deemed to …

Do infections have a role in the pathogenesis of Alzheimer disease?

…, TE Golde, MT Heneka, B Readhead - Nature Reviews …, 2020 - nature.com
… The main reason for this change is probably an article by Readhead et al. describing the …
Ben Readhead. I suspect that the interest has been present in ‘latent’ form for some time …

Gene expression elucidates functional impact of polygenic risk for schizophrenia

…, KK Dang, A Browne, C Lu, L Xie, B Readhead… - Nature …, 2016 - nature.com
… (b) Quantification of head size phenotype in each treatment condition as compared to
control embryos for furin MO (N control = 76, N furin MO = 66, P = 5.32 × 10 −20 ), TSNARE1 (N …

Computational and experimental advances in drug repositioning for accelerated therapeutic stratification

K Shameer, B Readhead… - Current topics in medicinal …, 2015 - ingentaconnect.com
… , doxorubicin, vincristine and prednisone) for the treatment of diffuse large B-cell lymphoma
… on off-targeting of the molecule agains EGF receptor and cytosolic protein kinase B [129] …

[PDF][PDF] Multiscale analysis of independent Alzheimer's cohorts finds disruption of molecular, genetic, and clinical networks by human herpesvirus

B Readhead, JV Haure-Mirande, CC Funk… - Neuron, 2018 - cell.com
… –E) Regulatory networks built across EC and HIP samples showed differences in gene
drivers for preclinical AD versus control networks (B) including many AD associated genes (C), …

Necroptosis activation in Alzheimer's disease

…, MJ Huentelman, WS Liang, B Readhead… - Nature …, 2017 - nature.com
… (b,c) Quantitative analyses of the blots revealed elevated levels of RIPK1 (t(21) = 3.444, P =
0.002 for RIPA; t(21) = 2.205, P = 0.038 for urea) and MLKL (t(21) = 2.443, P = 0.023 for RIPA…

[HTML][HTML] L1000CDS2: LINCS L1000 characteristic direction signatures search engine

…, NF Fernandez, AD Rouillard, B Readhead… - NPJ systems biology …, 2016 - nature.com
… (a, b) Histograms of the significance scores for the 8,301 signatures from the LJP5 and
LJP6 batches. (c) Correlation between the strength metrics for signatures computed by the two …

[PDF][PDF] A targetable GATA2-IGF2 axis confers aggressiveness in lethal prostate cancer

…, A Lee, B Readhead, X Chen, M Galsky, B Esteve… - Cancer cell, 2015 - cell.com
… (B) Representative colony-formation assays and quantifications … (B). (D) Flow cytometry
detection of Annexin V and PI in the same cells and following the same treatments described in (B

[PDF][PDF] Landscape of conditional eQTL in dorsolateral prefrontal cortex and co-localization with schizophrenia GWAS

…, A Topol, A Charney, B Readhead, B Zhang… - The American Journal of …, 2018 - cell.com
… þ , Figures 2A and 2C) or remained level (REMC brain-specific, Figure 2B). Though there …
(B) Same hypothetical GWAS and eQTL signatures after the all-but-one conditional eQTL …

Polygenic overlap between schizophrenia risk and antipsychotic response: a genomic medicine approach

DM Ruderfer, AW Charney, B Readhead… - The Lancet …, 2016 - thelancet.com
Background Therapeutic treatments for schizophrenia do not alleviate symptoms for all patients
and efficacy is limited by common, often severe, side-effects. Genetic studies of disease …