… Panel b shows the effects of KLF4 overexpression specifically in the squamous compartment.
Overexpression of KLF4 induces squamous dysplasia in mice, compared with wild-type …

This review addresses important issues of porcine reproductive and respiratory syndrome
virus (PRRSV) infection, immunity, pathogenesis, and control. Worldwide, PRRS is the most …

… Part b is adapted with permission from Stein, Barry E., and M. Alex Meredith., The Merging
of the Senses, Figure 8.1, © 1993 Massachusetts Institute of Technology, by permission of …

KLF4 (GKLF/EZF) encodes a transcription factor that is associated with both tumour suppression
and oncogenesis. We describe the identification of KLF4 in a functional genomic screen …

… The FRAP plots in Figure 3I include the same data and Figure S5B shows the bleaching
control. … (B) Density plot showing the length distribution of the loops called by HICCUPS ( …

We investigated genome folding across the eukaryotic tree of life. We find two types of three-dimensional
(3D) genome architectures at the chromosome scale. Each type appears and …

Cohesin's Smc1, Smc3, and Scc1 subunits form a tripartite ring that entraps sister DNAs.
Scc3, Pds5, and Rad61 (Wapl) are regulatory subunits that control this process. We describe …

Restoration of blood flow to an acutely ischemic lower limb may, paradoxically, result in
systemic complications and unexpected mortality. We investigated the effect of acute ischemia-…

… Interestingly, cohesin-mediated loop extrusion turns out to be vital also for the immunological
processes that ensure B cell and T cell receptor diversity, thereby facilitating our adaptive …

… b, Detailed view of the binding interface with SA2 residues in blue, SCC1 in green and CTCF
in magenta. c, d, Details … 2a, b), we suggest that this interaction stabilizes chromatin loops. …