User profiles for B. Striepen

Boris Striepen

Professor, University of Pennsylvania
Verified email at upenn.edu
Cited by 15286

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

…, WA Petri, JW Priest, DS Roos, B Striepen… - The Lancet Infectious …, 2015 - thelancet.com
Cryptosporidium spp are well recognised as causes of diarrhoeal disease during waterborne
epidemics and in immunocompromised hosts. Studies have also drawn attention to an …

Cell division in apicomplexan parasites

ME Francia, B Striepen - Nature Reviews Microbiology, 2014 - nature.com
b | The nucleus of apicomplexan parasites is highly structured. In particular, centromeres
and telomeres localize at the periphery of the nucleus. c | The daughter cell microtubule …

[HTML][HTML] Building the perfect parasite: cell division in apicomplexa

B Striepen, CN Jordan, S Reiff… - PLoS pathogens, 2007 - journals.plos.org
… Several observations are consistent with an association of this ring with myosin B/C [32,49];
however, the actin-destabilizing drug cytochalasin D does not interfere with parasite division […

Nuclear-encoded proteins target to the plastid in Toxoplasma gondii and Plasmodium falciparum

…, PJ Keeling, RGK Donald, B Striepen… - Proceedings of the …, 1998 - National Acad Sciences
… (B) Secondary endosymbiotic plastid origin involves a heterotrophic eukaryote
phagocytozing a photosynthetic eukaryote produced by primary endosymbiosis. The secondary …

[PDF][PDF] Serotonin reduction in post-acute sequelae of viral infection

…, LA Litzky, M Feldman, J Henao-Mejia, B Striepen… - Cell, 2023 - cell.com
B Megakaryocyte analysis B Platelet and platelet-rich-… B Metabolite and soluble factor
measurements B BCA protein quantification B RNA sequencing analysis of human organoids B

[PDF][PDF] Dynamics of neutrophil migration in lymph nodes during infection

…, SW Chan, H Satija, K Camfield, H Aaron, B Striepen… - Immunity, 2008 - cell.com
… (B) A 20 um frozen section of a draining lymph node from a mouse bearing the LysGFP
reporter (green) 4 hr after an earflap injection with RFP (red) parasites and stained with CD169 (…

[HTML][HTML] CD40 induces macrophage anti–Toxoplasma gondii activity by triggering autophagy-dependent fusion of pathogen-containing vacuoles and …

…, MJ Gubbels, B Striepen… - The Journal of …, 2006 - Am Soc Clin Investig
… Expression of late endosomal and lysosomal markers (A) or early endosomal markers (B)
was examined by immunofluorescence at different times after challenge. Opsonized …

[HTML][HTML] Genetic modification of the diarrhoeal pathogen Cryptosporidium parvum

…, CJ Studstill, Y Bar-Peled, MJ Cipriano, B Striepen - Nature, 2015 - nature.com
b, Translational fusions were constructed placing Neo at the amino or carboxy terminus of
Nluc. Nluc–Neo shows luciferase activity, albeit at a reduced level when compared to Nluc …

Toxoplasma gondii Tic20 is essential for apicoplast protein import

…, S Agrawal, BM Humbel, B Striepen - Proceedings of the …, 2008 - National Acad Sciences
… (B) Schematic depiction of the three protein import assays used in this work. We
measured cleavage of preprotein leader sequences by the stromal processing peptidase (SPP), …

Apicoplast fatty acid synthesis is essential for organelle biogenesis and parasite survival in Toxoplasma gondii

…, K Masek, C A. Hunter, B Striepen - Proceedings of the …, 2006 - National Acad Sciences
… (A and B) Immunofluorescence (A) and Western blot (B) analysis of parent and mutant cells
with antibody to lipoylated PDH-E2 (2H-4C8). ATc treatment of the mutant abolishes PDH …