User profiles for B. Vanderperre
 | Benoît VanderperreAssistant Professor, Université du Québec à Montréal Verified email at usherbrooke.ca Cited by 1118 |
Mitochondrial pyruvate import and its effects on homeostasis
B Vanderperre, T Bender, ERS Kunji… - Current opinion in cell …, 2015 - Elsevier
Highlights • Two inner membrane proteins compose the mitochondrial pyruvate carrier (MPC)
complex. • Defects in MPC's activity perturb cellular and whole-body metabolic …
complex. • Defects in MPC's activity perturb cellular and whole-body metabolic …
The endo-lysosomal system in Parkinson's disease: Expanding the horizon
A Muraleedharan, B Vanderperre - Journal of Molecular Biology, 2023 - Elsevier
… ) ARSAvii) ASAH1viii) SMPD1ix) HEXA/B cleavage products give rise to the sphingolipid
activator proteins/SAP (saposins) A, B, C, and D that regulate sphingolipid metabolismencodes …
activator proteins/SAP (saposins) A, B, C, and D that regulate sphingolipid metabolismencodes …
[HTML][HTML] Direct detection of alternative open reading frames translation products in human significantly expands the proteome
B Vanderperre, JF Lucier, C Bissonnette, J Motard… - PloS one, 2013 - journals.plos.org
… (B) Average peptide intensity plot of both the reference and alternative proteins that were
co-expressed from 42 genes. (C) Same as (A) with colon cell lines. (D) Venn diagram showing …
co-expressed from 42 genes. (C) Same as (A) with colon cell lines. (D) Venn diagram showing …
SMPD1 mutations, activity, and α‐synuclein accumulation in Parkinson's disease
Background SMPD1 (acid‐sphingomyelinase) variants have been associated with Parkinson's
disease in recent studies. The objective of this study was to further investigate the role of …
disease in recent studies. The objective of this study was to further investigate the role of …
Deep transcriptome annotation enables the discovery and functional characterization of cryptic small proteins
… comparisons (organism A vs organism B, organism B vs organism A), plus two self-self
runs (organism A vs organism A, organism B vs organism B). BLAST homology inference was …
runs (organism A vs organism A, organism B vs organism B). BLAST homology inference was …
Genetic, Structural, and Functional Evidence Link TMEM175 to Synucleinopathies
…, B Vanderperre, B Ouled Amar Bencheikh… - Annals of …, 2020 - Wiley Online Library
Objective The TMEM175/GAK/DGKQ locus is the 3rd strongest risk locus in genome‐wide
association studies of Parkinson disease (PD). We aimed to identify the specific disease‐…
association studies of Parkinson disease (PD). We aimed to identify the specific disease‐…
[PDF][PDF] Monitoring mitochondrial pyruvate carrier activity in real time using a BRET-based biosensor: investigation of the Warburg effect
V Compan, S Pierredon, B Vanderperre, P Krznar… - Molecular cell, 2015 - cell.com
… (B) Representative images showing the subcellular localization of hMPC1 and hMPC2
tagged with Venus. 2 days after transfection with either MPC1-Venus or MPC2-Venus (green), …
tagged with Venus. 2 days after transfection with either MPC1-Venus or MPC2-Venus (green), …
Quantification of tau phosphorylated at threonine 181 in human cerebrospinal fluid: a sandwich ELISA with a synthetic phosphopeptide for standardization
…, P Davidsson, E Van Kerschaver, B Van Der Perre… - Neuroscience …, 2000 - Elsevier
Hyperphosphorylation of the microtubule-associated protein tau is specifically found in
those brain cells affected in several tauopathies. Tau has also been consistently found to be …
those brain cells affected in several tauopathies. Tau has also been consistently found to be …
[PDF][PDF] Rapid macropinocytic transfer of α-synuclein to lysosomes
…, CE Zorca, I Shlaifer, EDC Pellitero, B Vanderperre… - Cell Reports, 2022 - cell.com
… B PFF endocytosis assays B PFF long-term endocytosis assays B Macropinocytic
inhibitors B LatA inhibition in dopaminergic NPCs B Lysosomal immunoprecipitation B PFF …
inhibitors B LatA inhibition in dopaminergic NPCs B Lysosomal immunoprecipitation B PFF …
[HTML][HTML] Embryonic lethality of mitochondrial pyruvate carrier 1 deficient mouse can be rescued by a ketogenic diet
B Vanderperre, S Herzig, P Krznar, M Hörl… - PLoS …, 2016 - journals.plos.org
… (B) Genotype distribution of pups derived from heterozygous MPC1 gt/+ breeding. (C)
Weight gain profiles of MPC1 +/+ and MPC1 gt/+ mice from post-natal week 3 to week 10. (D) …
Weight gain profiles of MPC1 +/+ and MPC1 gt/+ mice from post-natal week 3 to week 10. (D) …