User profiles for C. A. Darby
Charlotte A DarbyTakeda Pharmaceuticals Verified email at jhu.edu Cited by 7285 |
Piercing the dark matter: bioinformatics of long-range sequencing and mapping
Several new genomics technologies have become available that offer long-read sequencing
or long-range mapping with higher throughput and higher resolution analysis than ever …
or long-range mapping with higher throughput and higher resolution analysis than ever …
Recruitment experience in clinical trials: literature summary and annotated bibliography
DB Hunninghake, CA Darby, JL Probstfield - Controlled clinical trials, 1987 - Elsevier
A literature review was conducted to determine what problems exist in accruing adequate
numbers of patients for clinical trials. Accrual rates are often not clearly reported, and most …
numbers of patients for clinical trials. Accrual rates are often not clearly reported, and most …
Design and characterization of a computationally optimized broadly reactive hemagglutinin vaccine for H1N1 influenza viruses
DM Carter, CA Darby, BC Lefoley, CJ Crevar… - Journal of …, 2016 - Am Soc Microbiol
… CA/09 VLPs had fewer and more irregular surface glycoproteins (Fig. 3D). All wild-type
and COBRA VLPs were designed to express a mismatched NA from the N3 subtype (taxonomy …
and COBRA VLPs were designed to express a mismatched NA from the N3 subtype (taxonomy …
Elicitation of protective antibodies against a broad panel of H1N1 viruses in ferrets preimmune to historical H1N1 influenza viruses
DM Carter, CA Darby, SK Johnson, MA Carlock… - Journal of …, 2017 - Am Soc Microbiol
… An ELISA utilizing a chimeric HA protein (cH6/1) was used to assess antibody reactivity
against the conserved stem region of A/California/07/09 (CA/09). In brief, Immulon 4HBX plates (…
against the conserved stem region of A/California/07/09 (CA/09). In brief, Immulon 4HBX plates (…
Xenolog classification
Motivation Orthology analysis is a fundamental tool in comparative genomics. Sophisticated
methods have been developed to distinguish between orthologs and paralogs and to …
methods have been developed to distinguish between orthologs and paralogs and to …
[HTML][HTML] LRSim: a linked-reads simulator generating insights for better genome partitioning
Linked-read sequencing, using highly-multiplexed genome partitioning and barcoding, can
span hundreds of kilobases to improve de novo assembly, haplotype phasing, and other …
span hundreds of kilobases to improve de novo assembly, haplotype phasing, and other …
Vargas: heuristic-free alignment for assessing linear and graph read aligners
Motivation Read alignment is central to many aspects of modern genomics. Most aligners
use heuristics to accelerate processing, but these heuristics can fail to find the optimal …
use heuristics to accelerate processing, but these heuristics can fail to find the optimal …
scHLAcount: allele-specific HLA expression from single-cell gene expression data
Bulk RNA sequencing studies have demonstrated that human leukocyte antigen (HLA)
genes may be expressed in a cell type-specific and allele-specific fashion. Single-cell gene …
genes may be expressed in a cell type-specific and allele-specific fashion. Single-cell gene …
Analysis of the Chunked Reading Test and reading comprehension
RP Carver, CA Darby Jr - Journal of Reading Behavior, 1972 - journals.sagepub.com
The newly developed Chunked Reading Test was further analyzed by correlating the
scores on this test with three other standardized reading tests—Davis Reading Test, Nelson-Denny …
scores on this test with three other standardized reading tests—Davis Reading Test, Nelson-Denny …
DEVELOPMENT AND EVALUATION OF A TEST OF INFORMATION STORAGE DURING READING1
RP Carver, CA Darby Jr - Journal of Educational Measurement, 1971 - Wiley Online Library
Previous research has suggested potential advantages for a new type of item for measuring
comprehension in reading and listening. The test items are called “chunked” and consist of …
comprehension in reading and listening. The test items are called “chunked” and consist of …