User profiles for C. C. Collins

Colin Collins, PhD

Professor of Urologic Sciences, University of British Columbia and Vancouver Prostate …
Verified email at prostatecentre.com
Cited by 34234

Vision substitution by tactile image projection

P Bach-y-Rita, CC Collins, FA Saunders, B White… - Nature, 1969 - nature.com
WE describe here a vision substitution system which is being developed as a practical aid
for the blind and as a means of studying the processing of afferent information in the central …

Cancer‐generated lactic acid: a regulatory, immunosuppressive metabolite?

SYC Choi, CC Collins, PW Gout… - The Journal of …, 2013 - Wiley Online Library
The common preference of cancers for lactic acid‐generating metabolic energy pathways
has led to proposals that their reprogrammed metabolism confers growth advantages such as …

[HTML][HTML] Lessons from patient-derived xenografts for better in vitro modeling of human cancer

SYC Choi, D Lin, PW Gout, CC Collins, Y Xu… - Advanced drug delivery …, 2014 - Elsevier
The development of novel cancer therapeutics is often plagued by discrepancies between
drug efficacies obtained in preclinical studies and outcomes of clinical trials. The …

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

…, ID Krantz, YU Deng, A Genin, AB Banta, CC Collins… - Nature …, 1997 - nature.com
c, The proband and mother from family 3 demonstrate an HMA band shift in the "C" region.
SSCP analysis … c, No band shifts were observed on heteroduplex analysis with the A, B, …

Molecular characterization of neuroendocrine prostate cancer and identification of new drug targets

…, KJ Pienta, AM Chinnaiyan, Y Wang, CC Collins… - Cancer discovery, 2011 - AACR
Neuroendocrine prostate cancer (NEPC) is an aggressive subtype of prostate cancer that
most commonly evolves from preexisting prostate adenocarcinoma (PCA). Using next-…

[PDF][PDF] Pharmacologic weakening of extraocular muscles

…, A ROSENBAUM, CC COLLINS - … & Visual Science, 1973 - iovs.arvojournals.org
Currently, the correction of nonaccommodative strabismus involves surgical manipulation to
loosen or tighten extraocular muscles to balance the forces and align the eyes. The present …

Genomic hallmarks of localized, non-indolent prostate cancer

…, A Dal Pra, L Lacombe, CC Collins, C Sahinalp… - Nature, 2017 - nature.com
Prostate tumours are highly variable in their response to therapies, but clinically available
prognostic factors can explain only a fraction of this heterogeneity. Here we analysed 200 …

[BOOK][B] Camillo Sitte: the birth of modern city planning

GR Collins, C Sitte, CC Collins - 2006 - books.google.com
Collins and Christiane Crasemann Collins includes Sitte's original drawings and plates in
a format resembling the original publication. The authors place Sitte's work within the context …

Spatial genomic heterogeneity within localized, multifocal prostate cancer

…, LD Stein, N Fleshner, SP Shah, CC Collins… - Nature …, 2015 - nature.com
Herein we provide a detailed molecular analysis of the spatial heterogeneity of clinically
localized, multifocal prostate cancer to delineate new oncogenes or tumor suppressors. We …

Androgen receptor gene aberrations in circulating cell-free DNA: biomarkers of therapeutic resistance in castration-resistant prostate cancer

…, EJ Small, Y Wang, ME Gleave, CC Collins… - Clinical cancer …, 2015 - AACR
Purpose: Although novel agents targeting the androgen–androgen receptor (AR) axis have
altered the treatment paradigm of metastatic castration-resistant prostate cancer (mCRPC), …