The chick embryo has a long and distinguished history as a major model system in developmental
biology and has also contributed major concepts to immunology, genetics, virology, …

… and Whitman,1997; Christen and Slack,1999), which might partly account for the apparent
`sufficiency'of BMP inhibition for neural induction in animal cap assays(Streit and Stern, 1999c…

… Davies, GMW Cook, RJ Keynes & CD Stern, unpublished observations). The properties of
the cytotactin-binding proteoglycan described by Tan et al. (1987) may also be relevant here: …

OpenMM is a molecular dynamics simulation toolkit with a unique focus on extensibility. It
allows users to easily add new features, including forces with novel functional forms, new …

Contact inhibition of locomotion was discovered by Abercrombie more than 50 years ago
and describes the behaviour of fibroblast cells confronting each other in vitro, where they …

During neural induction, the ‘organizer’ of the vertebrate embryo instructs neighbouring
ectodermal cells to become nervous system rather than epidermis. This process is generally …

Fate maps of chick Hensen’s node were generated using Dil and the lineage of individual
cells studied by intracellular injection of lysine-rhodamine-dextran (LRD). The cell types …

We have investigated the role of Bone Morphogenetic Protein 4 (BMP-4) and a BMP antagonist,
chordin, in primitive streak formation and neural induction in amniote embryos. We show …

Although there is good evidence that growing axons can be guided by specific cues during
the development of the vertebrate peripheral nervous system 1 , little is known about the …

THE diencephalon is a complex integration centre and intricate relay station of the vertebrate
brain 1–3 . Its development involves the generation of great cellular diversity and neuronal …