… The answer is provided in a paper by Christian Doeller, Caswell Barry and Neil Burgess
in which single-unit recordings of grid cells in freely moving rats were combined with whole-…

In human and non-human animals, conceptual knowledge is partially organized according
to low-dimensional geometries that rely on brain structures and computations involved in …

BACKGROUND Ever since Edward Tolman’s proposal that comprehensive cognitive maps
underlie spatial navigation and, more generally, psychological functions, the question of how …

A growing body of work is investigating the use of mental maps during decision-making. Here
we discuss how decision-making organizes experiences according to an internal model of …

Alzheimer’s disease (AD) manifests with memory loss and spatial disorientation. AD
pathology starts in the entorhinal cortex, making it likely that local neural correlates of spatial …

The cortical reinstatement hypothesis of memory retrieval posits that content-specific cortical
activity at encoding is reinstated at retrieval. Evidence for cortical reinstatement was found …

Entorhinal grid cells map the local environment, but their involvement beyond spatial
navigation remains elusive. We examined human functional MRI responses during a highly …

10.7554/eLife.17089.001 Anticipating the future is a key motif of the brain, possibly supported
by mental simulation of upcoming events. Rodent single-cell recordings suggest the ability …

How the memory systems centered on the hippocampus and dorsal striatum interact to
support behavior remains controversial. We used functional MRI while people learned the …

The hippocampal formation encodes maps of the physical environment [1–5]. A key question
in neuroscience is whether its spatial coding principles also provide a universal metric for …