[HTML][HTML] The relative contributions of infectious and mitotic spread to HTLV-1 persistence
…, L Boelen, CRM Bangham, B Asquith - PLoS computational …, 2020 - journals.plos.org
Human T-lymphotropic virus type-1 (HTLV-1) persists within hosts via infectious spread (de
novo infection) and mitotic spread (infected cell proliferation), creating a population structure …
novo infection) and mitotic spread (infected cell proliferation), creating a population structure …
[HTML][HTML] The efficiency of the human CD8+ T cell response: how should we quantify it, what determines it, and does it matter?
…, NK Seich al Basatena, B Asquith - PLoS computational …, 2012 - journals.plos.org
Multidisciplinary techniques, in particular the combination of theoretical and experimental
immunology, can address questions about human immunity that cannot be answered by other …
immunology, can address questions about human immunity that cannot be answered by other …
[HTML][HTML] KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection
Killer cell immunoglobulin-like receptors (KIRs) influence both innate and adaptive immunity.
But while the role of KIRs in NK-mediated innate immunity is well-documented, the impact …
But while the role of KIRs in NK-mediated innate immunity is well-documented, the impact …
Numb-associated kinases are required for SARS-CoV-2 infection and are cellular targets for antiviral strategies
… Pinsky a b , Luis Martinez-Sobrido c , Christopher RM Asquith g i , Aarthi Narayanan d , …
SGC-GAK-1, a 4-anilinoquinoline, (compound 11 in (Asquith et al., 2019a)) with potent anti-…
SGC-GAK-1, a 4-anilinoquinoline, (compound 11 in (Asquith et al., 2019a)) with potent anti-…
[HTML][HTML] Innate receptors modulating adaptive T cell responses: KIR-HLA interactions and T cell-mediated control of chronic viral infections
L Mora-Bitria, B Asquith - Immunogenetics, 2023 - Springer
Killer-cell immunoglobulin-like receptors (KIRs) are mainly expressed on natural killer (NK)
cells and are key regulators of innate immune responses. NK cells are the first responders in …
cells and are key regulators of innate immune responses. NK cells are the first responders in …
[HTML][HTML] HTLV-1: persistence and pathogenesis
► General method to identify the determinants of protective immunity and its application to
HTLV-1.► Observation made that “innate” KIR receptors enhance the HLA class I-restricted …
HTLV-1.► Observation made that “innate” KIR receptors enhance the HLA class I-restricted …
Short Communication An Interferon-γ ELISPOT Assay with Two Cytotoxic T Cell Epitopes Derived from HTLV-1 Tax Region 161-233 Discriminates HTLV-1 …
…, E González, M Tipismana, B Asquith… - AIDS Research and …, 2011 - liebertpub.com
… UDAsquith BQuantifying the impact of human immunodeficiency virus-1 escape from
cytotoxic T-lymphocytesPLoS Comput Biol20106e1000981. 27. Kadolsky UD and Asquith B: …
cytotoxic T-lymphocytesPLoS Comput Biol20106e1000981. 27. Kadolsky UD and Asquith B: …
Exploration and Development of a C–H-Activated Route to Access the [1, 2] Dithiolo [4, 3-b] indole-3 (4H)-thione Core and Related Derivatives
CRM Asquith, LS Konstantinova, GJ Tizzard… - Synlett, 2019 - thieme-connect.com
… Christopher RM Asquith * … 6 Asquith CR. M, Meli ML, Konstantinova LS, Laitinen T,
Poso A, Rakitin OA, Hofmann-Lehmann R, Allenspach K, Hilton ST. Bioorg. … 6 Asquith CR …
Poso A, Rakitin OA, Hofmann-Lehmann R, Allenspach K, Hilton ST. Bioorg. … 6 Asquith CR …
PIP4K2C inhibition reverses autophagic flux impairment induced by SARS-CoV-2
In search for broad-spectrum antivirals, we discovered a small molecule inhibitor, RMC-113,
that potently suppresses the replication of multiple RNA viruses including SARS-CoV-2 in …
that potently suppresses the replication of multiple RNA viruses including SARS-CoV-2 in …
[PDF][PDF] Photon, Jet and W/Z+ Jets Measurements with ATLAS
L Asquith - 2016 - cds.cern.ch
… Lily Asquith (University of Sussex) … lily.asquith@cern.ch … lily.asquith@cern.ch …