User profiles for C. S. Hansen

Christine Søholm Hansen

- Verified email at ssi.dk - Cited by 16566

Christian Stevns Hansen

- Verified email at regionh.dk - Cited by 2862

Christian Skodborg Hansen

- Verified email at byg.dtu.dk - Cited by 330

Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression

…, J Grove, LS Hall, E Hannon, CS Hansen, TF Hansen… - Nature …, 2018 - nature.com
Major depressive disorder (MDD) is a common illness accompanied by considerable
morbidity, mortality, costs, and heightened risk of suicide. We conducted a genome-wide …

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

…, KL Grasby, J Grove, OO Gudmundsson, CS Hansen… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Identification of common genetic risk variants for autism spectrum disorder

…, S Djurovic, AL Dumont, JI Goldstein, CS Hansen… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

…, E Sigurdsson, T Silagadze, CS Hansen… - Nature …, 2018 - nature.com
Schizophrenia is a debilitating psychiatric condition often associated with poor quality of life
and decreased life expectancy. Lack of progress in improving treatment outcomes has been …

[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders

…, J Haavik, H Hakonarson, CS Hansen… - Cell, 2019 - cell.com
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …

[HTML][HTML] The iPSYCH2012 case–cohort sample: new directions for unravelling genetic and environmental architectures of severe mental disorders

…, M Baekvad-Hansen, JB Poulsen, CS Hansen… - Molecular …, 2018 - nature.com
The Integrative Psychiatric Research (iPSYCH) consortium has established a large Danish
population-based Case–Cohort sample (iPSYCH2012) aimed at unravelling the genetic and …

The genetic architecture of depression in individuals of East Asian ancestry: a genome-wide association study

…, J Grove, LS Hall, CS Hansen, TF Hansen… - JAMA …, 2021 - jamanetwork.com
Importance Most previous genome-wide association studies (GWAS) of depression have used
data from individuals of European descent. This limits the understanding of the underlying …

Strengthening of old metallic structures in fatigue with prestressed and non-prestressed CFRP laminates

B Täljsten, CS Hansen, JW Schmidt - Construction and Building Materials, 2009 - Elsevier
Test results and theoretical considerations on four different configurations of strengthened
old steel plates with a centre notch loaded in fatigue are presented in this paper. The main …

[HTML][HTML] An epigenetic clock for gestational age at birth based on blood methylation data

…, M Bækvad-Hansen, J Bybjerg-Grauholm, CS Hansen… - Genome biology, 2016 - Springer
Background Gestational age is often used as a proxy for developmental maturity by clinicians
and researchers alike. DNA methylation has previously been shown to be associated with …

Early detection of diabetic kidney disease by urinary proteomics and subsequent intervention with spironolactone to delay progression (PRIORITY): a prospective …

…, TW Hansen, BJ von Scholten, CS Hansen… - The lancet Diabetes & …, 2020 - thelancet.com
Background Microalbuminuria is an early sign of kidney disease in people with diabetes and
indicates increased risk of cardiovascular disease. We tested whether a urinary proteomic …