Estrogen receptor is a key regulator of proliferation and differentiation in mammary epithelia
and represents a crucial prognostic indicator and therapeutic target in breast cancer. …

Purpose To conduct a comprehensive analysis of radiologist-made assessments of
glioblastoma (GBM) tumor size and composition by using a community-developed controlled …

The expression patterns of 7075 genes were analyzed in four conventional (clear cell) renal
cell carcinomas (RCC), one chromophobe RCC, and two oncocytomas using cDNA …

While numerous studies have implicated copy number variants (CNVs) in a range of neurological
phenotypes, the impact relative to disease severity has been difficult to ascertain due …

Prostate cancer is the most commonly diagnosed noncutaneous neoplasm and second most
common cause of cancer-related mortality in western men. To investigate the mechanisms …

Background Triple Negative subset of (TN) Breast Cancers (BC), a close associate of the
basal-like subtype (with limited discordance) is an aggressive form of the disease which …

The Cancer Genome Atlas (TCGA) project has generated gene expression data that divides
glioblastoma (GBM) into four transcriptional classes: proneural, neural, classical, and …

Pituitary adenomas comprise 10% of intracranial tumors and occur in about 20% of the
population. They cause significant morbidity by compression of regional structures or the …

SOX4 is a critical developmental transcription factor in vertebrates and is required for precise
differentiation and proliferation in multiple tissues. In addition, SOX4 is overexpressed in …

Protein phosphatase 2A (PP2A) is a multifunctional serine/threonine phosphatase that is
critical to many cellular processes including development, neuronal signaling, cell cycle …