Circulating microRNAs as stable blood-based markers for cancer detection
…, DW Lin, N Urban, CW Drescher… - Proceedings of the …, 2008 - National Acad Sciences
Improved approaches for the detection of common epithelial malignancies are urgently
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) …
needed to reduce the worldwide morbidity and mortality caused by cancer. MicroRNAs (miRNAs) …
Early diagnosis of ovarian carcinoma: is a solution in sight?
AM Lutz, JK Willmann, CW Drescher, P Ray… - Radiology, 2011 - pubs.rsna.org
Ovarian cancer is the most lethal of the gynecologic malignancies. Because ovarian cancer
symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well …
symptoms are subtle and nonspecific, the diagnosis is often delayed until the disease is well …
Biomarkers and strategies for early detection of ovarian cancer
…, CY Han, KH Lu, KS Anderson, CW Drescher… - … Biomarkers & Prevention, 2020 - AACR
Early detection of ovarian cancer remains an important unmet medical need. Effective
screening could reduce mortality by 10%–30%. Used individually, neither serum CA125 nor …
screening could reduce mortality by 10%–30%. Used individually, neither serum CA125 nor …
Development of an ovarian cancer symptom index: possibilities for earlier detection
BA Goff, LS Mandel, CW Drescher, N Urban, S Gough… - Cancer, 2007 - Wiley Online Library
BACKGROUND. Currently, screening for ovarian cancer is not recommended for the general
population. Targeting women with specific symptoms for screening has been evaluated …
population. Targeting women with specific symptoms for screening has been evaluated …
[HTML][HTML] Repertoire of microRNAs in epithelial ovarian cancer as determined by next generation sequencing of small RNA cDNA libraries
…, K O'Briant, AK Godwin, N Urban, CW Drescher… - PloS one, 2009 - journals.plos.org
Background MicroRNAs (miRNAs) are small regulatory RNAs that are implicated in cancer
pathogenesis and have recently shown promise as blood-based biomarkers for cancer …
pathogenesis and have recently shown promise as blood-based biomarkers for cancer …
Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: evidence supporting a mesothelial-to-epithelial transition
…, AP Ventura, AK Godwin, BY Karlan, CW Drescher… - Gynecologic …, 2010 - Elsevier
OBJECTIVE: Our objective was to characterize the expression and function of the miR-200
family of microRNAs (miRNA) in ovarian carcinogenesis. METHODS: We used qRT-PCR to …
family of microRNAs (miRNA) in ovarian carcinogenesis. METHODS: We used qRT-PCR to …
High‐throughput sequencing of T‐cell receptors reveals a homogeneous repertoire of tumour‐infiltrating lymphocytes in ovarian cancer
…, CS Carlson, CW Drescher… - The Journal of …, 2013 - Wiley Online Library
The cellular adaptive immune system mounts a response to many solid tumours mediated
by tumour‐infiltrating T lymphocytes ( TILs ). Basic measurements of these TILs , including …
by tumour‐infiltrating T lymphocytes ( TILs ). Basic measurements of these TILs , including …
Use of a Symptom Index, CA125, and HE4 to predict ovarian cancer
…, KA Lowe, N Scholler, L Bergan, CW Drescher… - Gynecologic …, 2010 - Elsevier
BACKGROUND.: Prior studies suggest that combining the Symptom Index (SI) with a serum
HE4 test or a CA125 test may improve prediction of ovarian cancer. However, these three …
HE4 test or a CA125 test may improve prediction of ovarian cancer. However, these three …
Robotic surgery in gynecologic oncology: program initiation and outcomes after the first year with comparison with laparotomy for endometrial cancer staging
DS Veljovich, PJ Paley, CW Drescher… - American Journal of …, 2008 - Elsevier
OBJECTIVE: The objective of the study was to evaluate outcomes during the first year of a
robotic surgery program in gynecologic oncology. STUDY DESIGN: We studied the initiation of …
robotic surgery program in gynecologic oncology. STUDY DESIGN: We studied the initiation of …
Bead-based ELISA for validation of ovarian cancer early detection markers
N Scholler, M Crawford, A Sato, CW Drescher… - Clinical cancer …, 2006 - AACR
Purpose: Efforts to validate ovarian cancer early detection biomarkers with immunoassays
are challenged by the limited specimen volumes available. We sought to develop a specimen-…
are challenged by the limited specimen volumes available. We sought to develop a specimen-…