… Emodepside appears to activate NO and protein kinase C signalling pathways to produce
slow activation of voltage-activated Ca-dependent SLO-1-like K channels leading to paralysis …

Reports of loss-of-efficacy (LOE) events in dogs infected with Dirofilaria immitis despite
adherence to accepted prophylaxis regimens with a macrocyclic lactone anthelmintic are …

Scientists in sleep and circadian rhythms, public health experts, healthcare providers,
partners, and stakeholders convened in 2020 for a 2-day meeting organized by the Canadian …

… Efficacies were calculated as % efficacy = (C − T)/C × 100, where C and T are the
arithmetic means of live parasites in the control group and treated group, respectively. …

Background Treatment of onchocerciasis using mass ivermectin administration has reduced
morbidity and transmission throughout Africa and Central/South America. Mass drug …

… a commercial pharmaceutical firm; b) residence in an area identified as a `hotspot’ of
suspected drug resistance in the 2009 statewide veterinary practitioner survey of LOE cases [2]; c) …

… Denaturation was performed at 94 C for 45 s, annealing at 56 C for 45 s and extension at
68 C for 2 min for 35 cycles. High Fidelity Platinum ® Taq DNA polymerase (Invitrogen, …

… C for 4 min; followed by 40 cycles of 95 C for 15 s, 47 C for 15 s and 70 C for 30 s, with a final
extension step at 70 C … The reactions were heated at 80 C for 2 min, placed on ice, and 2.5 …

… TCG TTG GAA TTT GC 3′ at Tm = 54C. PCR products were analyzed by restriction fragment
length polymorphism, based on C/T polymorphism apparent in the EST database, using …

… Denaturation was performed at 94 C for 45 s, annealing at 56 C for 45 s and extension at 68
C for 2 min for 35 cycles. PCR amplification was confirmed by electrophoresis through a 1% …