Tuberculosis, an ancient disease of mankind, remains one of the major infectious causes of
human death. We examine newly discovered facets of tuberculosis pathogenesis and …

Background Various treatments of osteoarthritis ( OA ) have been described, including use
of nutraceuticals. Objectives To review systematically the literature about the effects of …

… c, Percentage of infected macrophages that were iNOS positive in the HBV at 3 dpi with
80 wild-type, ΔmmpL7 or Δerp M. marinum. Representative of three separate experiments. …

Neutrophils are typically the first responders in host defense against invading pathogens,
which they destroy by both oxidative and nonoxidative mechanisms. However, despite a …

Mycobacterium tuberculosis (Mtb) enters the host in aerosol droplets deposited in lung alveoli,
where the bacteria first encounter lung-resident alveolar macrophages. We studied the …

… (C) Mean number of neutrophils recruited to the hindbrain ventricle after injection of $100 …
(A–C) Representative confocal images of the spinal cord injection site (upper; scale bar, 10 mm…

Immune control of persistent infection with Mycobacterium tuberculosis (Mtb) requires a
sustained pathogen-specific CD4 T cell response; however, the molecular pathways governing …

A zebrafish genetic screen for determinants of susceptibility to Mycobacterium marinum
identified a hypersusceptible mutant deficient in lysosomal cysteine cathepsins that manifests …

Understanding how veterinary practitioners make clinical decisions, and how they use
scientific information to inform their decisions, is important to optimize animal care, client …

Anergy, a condition in which cells persist in the periphery but are unresponsive to antigen, is
responsible for silencing many self-reactive B cells. Loss of anergy is known to contribute to …