The nuclear import of proteins into the cell nucleus involves the recognition of a nuclear
localization signal sequence, borne by the protein to be transported, by complex molecules …

… The reaction mixtures were then analyzed by PAGE at 4 C using a 12% polyacrylamide gel
in a 0.5× Tris borate buffer (45 mm Tris borate and 1 mm EDTA). The gels were exposed to …

Iodide has direct effects on thyroid function. Several iodinated lipids are biosynthesized by
the thyroid and they were postulated as intermediaries in the action of iodide. Among them, 2-…

The DNA sequences involved in transcription control by a cAMP-dependent mechanism
have been localized in the thyroglobulin gene promoter region by a functional assay. The …

Background A partial cDNA clone from dog thyroid presenting a very significant similarity
with an uncharacterized mouse EST sequence was isolated fortuitously. We report here the …

The N‐terminal end of thyroid transcription factor‐1 (TTF‐1) homeodomain is composed of
a stretch of five basic amino‐acids that is conserved in both POU‐ and NK2‐class …

The THOX and DUOXA genes encode components of the oxidative machinery involved in
thyroid hormone biosynthesis. Both of these genes are duplicated in mammalian genomes …

Thyroid transcription factor-1 (TTF-1) is a key regulator of thyroid development and function.
In order to identify the genes whose expression depends on TTF-1 transcriptional activity …

Thyroid Oxidases (ThOX/DUOX) genes encode proteins that are thought to play a crucial
role in the biosynthesis of thyroid hormone by providing the oxidizing agent required to allow …

The DNA sequences corresponding to a DNasel-hypersensitive region identified previously
in bovine thyroglobulin gene chromatin (Hansen et al. (1988) Eur. J. Biochem. 178, 387–393…