We report the updated classification of primary immunodeficiencies compiled by the Primary
Immunodeficiency Expert Committee (PID EC) of the International Union of Immunological …

Human immunoglobulin prepared for intravenous administration (IGIV) has a number of
important uses in the treatment of disease. Some of these are in diseases for which acceptable …

Although secretory immunoglobulin A (IgA) is important in mucosal immunity, selective IgA
deficiency is the most common primary immunodeficiency of humans. In most cases this …

Four homosexual men presented with gradually enlarging perianal ulcers, from which herpes
simplex virus was cultured. Each patient had a prolonged course characterized by weight …

Here, we describe a serological enzyme-linked immunosorbent assay for the screening and
identification of human SARS-CoV-2 seroconverters. This assay does not require the …

Common variable immunodeficiency (CVI) is a primary immunodeficiency disease
characterized by reduced serum immunoglobulins and heterogeneous clinical features. In these …

The chronic Epstein-Barr virus syndrome is a poorly defined symptom complex characterized
primarily by chronic or recurrent debilitating fatigue and various combinations of other …

We report the updated classification of Inborn Errors of Immunity/Primary Immunodeficiencies,
compiled by the International Union of Immunological Societies Expert Committee. This …

Beginning in 1970, a committee was constituted under the auspices of the World Health
Organization (WHO) to catalog primary immunodeficiencies. Twenty years later, the International …

Neutrophils use immunoglobulins to clear antigen, but their role in immunoglobulin production
is unknown. Here we identified neutrophils around the marginal zone (MZ) of the spleen, …