Contemporary practices for mechanical oral hygiene to prevent periodontal disease

S Sälzer, C Graetz, CE Dörfer, DE Slot… - Periodontology …, 2020 - Wiley Online Library
It is well established that dental plaque on teeth leads to gingivitis and periodontitis, and that
several mechanical and chemical methods of plaque control can prevent gingivitis. The aim …

Predictors for tooth loss in periodontitis patients: Systematic review and meta‐analysis

…, J Krois, K Fawzy El Sayed, C Graetz… - Journal of Clinical …, 2019 - Wiley Online Library
Aim A range of predictors for tooth loss in periodontitis patients have been reported. We
performed a systematic review and meta‐analysis to assess the consistency and magnitude of …

Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis

…, D Galimberti, C Gieger, PA Gourraud, C Graetz… - Nature …, 2013 - nature.com
Using the ImmunoChip custom genotyping array, we analyzed 14,498 subjects with multiple
sclerosis and 24,091 healthy controls for 161,311 autosomal variants and identified 135 …

Retention of questionable and hopeless teeth in compliant patients treated for aggressive periodontitis

C Graetz, CE Dörfer, M Kahl, T Kocher… - Journal of clinical …, 2011 - Wiley Online Library
Retention of questionable and hopeless teeth in compliant patients treated for aggressive
periodontitis - Graetz - 2011 - Journal of Clinical Periodontology - Wiley Online Library …

[PDF][PDF] Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls

…, A Franke, A Goris, PA Gourraud, C Graetz… - The American Journal of …, 2013 - cell.com
Multiple sclerosis (MS) is an inflammatory CNS disease with a substantial genetic component,
originally mapped to only the human leukocyte antigen (HLA) region. In the last 5 years, a …

Novel multiple sclerosis susceptibility loci implicated in epigenetic regulation

…, A Berthele, A Chan, C Gasperi, R Gold, C Graetz… - Science …, 2016 - science.org
We conducted a genome-wide association study (GWAS) on multiple sclerosis (MS)
susceptibility in German cohorts with 4888 cases and 10,395 controls. In addition to associations …

Peri‐implantitis versus periodontitis: functional differences indicated by transcriptome profiling

…, BE Beck‐Broichsitter, C Graetz… - … implant dentistry and …, 2014 - Wiley Online Library
Background Periodontitis and Periimplantitis are oftentimes discussed as one entity, which
is reflected by therapeutical as well as by scientific approaches. It is unclear, to which extent …

A genome-wide association study identifies nucleotide variants at SIGLEC5 and DEFA1A3 as risk loci for periodontitis

…, Y Jockel-Schneider, C Graetz… - Human molecular …, 2017 - academic.oup.com
Periodontitis is one of the most common inflammatory diseases, with a prevalence of 11%
worldwide for the severe forms and an estimated heritability of 50%. The disease is …

The Multiple Sclerosis Genomic Map: Role of peripheral immune cells and resident microglia in susceptibility

…, A Berthele, V Biberacher, D Buck, C Gasperi, C Graetz… - BioRxiv, 2017 - biorxiv.org
We assembled and analyzed genetic data of 47,351 multiple sclerosis (MS) subjects and
68,284 control subjects and establish a reference map of the genetic architecture of MS that …

Comparison of periodontitis patients' classification in the 2018 versus 1999 classification

C Graetz, L Mann, J Krois, S Sälzer… - Journal of clinical …, 2019 - Wiley Online Library
… this cohort were hence graded C) and/or the presence of a diabetes mellitus diagnosis (as
we did not have data on the HbA1c, we conservatively assigned grade C for all patients with …