… genes c-fos and c-jun in quiescent fibroblasts stimulated with growth factors, phorbol esters,
as well as phosphatase and protein synthesis inhibitors [41]. In contrast to global mitotic …

… Distinct additional domains are found only in certain species, for example a Cterminal
extension of unknown function in Drosophila. The HDAC1/HDAC2 protein is a target for various …

Systematic analysis of histone modifications has revealed a plethora of posttranslational
modifications that mediate changes in chromatin structure and gene expression. Histone …

… Immunoprecipitated complexes on protein A-agarose beads were incubated at 30 C for 1
h with [ 3 H]acetate-labelled chicken erythrocyte histones. The reaction was stopped by …

Histone deacetylases (HDACs) modulate chromatin structure and transcription, but little is
known about their function in mammalian development. HDAC1 was implicated previously in …

… Previously we have shown that the C terminus of Sp1 is necessary for the interaction with …
HDAC1 is associated with Sp1 and binds directly to the C-terminal part of Sp1 that was …

… To test whether the absence of HDAC1 and increased transcription affect the nucleosome
density, we also performed ChIP analyses with an antibody that recognizes the C terminus of …

Histone deacetylases (HDACs) regulate gene expression by deacetylating histones and
also modulate the acetylation of a number of nonhistone proteins, thus impinging on various …

… All cell lines were cultured in a humidified 37C incubator with 5% CO 2 . … Grausenburger,
and C. Seiser, unpublished data), perhaps because of a possible checkpoint activation in these …

… The p53 protein binds directly to the C terminus of Sp1, a domain which was previously …
simultaneous dissociation of HDAC1 from the C terminus of Sp1. Chromatin immunoprecipitation …