The accurate identification and description of the genes in the human and mouse genomes
is a fundamental requirement for high quality analysis of data informing both genome biology …

The GENCODE project annotates human and mouse genes and transcripts supported by
experimental data with high accuracy, providing a foundational resource that supports genome …

… (C) Effects of SNVs at interaction interfaces on interactions of WASP with other proteins
tested by Y2H experiments. Wild-type (WT) WASP interacts with all proteins shown, whereas …

The transcriptome is the readout of the genome. Identifying common features in it across distant
species can reveal fundamental principles. To this end, the ENCODE and modENCODE …

… (c) A duplicated pseudogene PDZ domain containing 1 pseudogene 1 (PDZK1P1; HAVANA
gene ID: OTTHUMG00000013746) and a spliced transcript model with nine exons. (d,e) …

We report full-length draft de novo genome assemblies for 16 widely used inbred mouse strains
and find extensive strain-specific haplotype variation. We identify and characterize 2,567 …

GENCODE produces high quality gene and transcript annotation for the human and mouse
genomes. All GENCODE annotation is supported by experimental data and serves as a …

Infection by the severe acute respiratory syndrome (SARS) coronavirus-2 (SARS-CoV-2) is
the causative agent of a new disease (COVID-19). The risk of severe COVID-19 is increased …

Pseudogenes are commonly labeled as “junk DNA” given their perceived nonfunctional status.
However, the advent of large-scale genomics projects prompted a revisit of pseudogene …

Understanding the mechanisms driving lineage-specific evolution in both primates and
rodents has been hindered by the lack of sister clades with a similar phylogenetic structure …