User profiles for C. Wilhelm-Benartzi
Charlotte S. Wilhelm-BenartziCardiff University Verified email at cardiff.ac.uk Cited by 3963 |
Whole–genome characterization of chemoresistant ovarian cancer
… Asterisk indicates statistical significance of C(C>T)C using a test of equal or given
proportions across the cohort after a Fisher’s exact test (two-sided) on individual cases (P <0.05). …
proportions across the cohort after a Fisher’s exact test (two-sided) on individual cases (P <0.05). …
Plasma antibodies to oral bacteria and risk of pancreatic cancer in a large European prospective cohort study
DS Michaud, J Izard, CS Wilhelm-Benartzi, DH You… - Gut, 2013 - gut.bmj.com
Objective Examine the relationship between antibodies to 25 oral bacteria and pancreatic
cancer risk in a prospective cohort study. Design We measured antibodies to oral bacteria in …
cancer risk in a prospective cohort study. Design We measured antibodies to oral bacteria in …
Candidate DNA methylation drivers of acquired cisplatin resistance in ovarian cancer identified by methylome and expression profiling
… ) and amplification parameters: 95 C for 3 min, 42 cycles of 95 C for 10 s, 60 C for 10 s and
72 C for 30 s, followed by 95 C for 10 s and temperature increments from 72–95 C for 5 s. …
72 C for 30 s, followed by 95 C for 10 s and temperature increments from 72–95 C for 5 s. …
Poised epigenetic states and acquired drug resistance in cancer
Epigenetic events, which are somatically inherited through cell division, are potential drivers
of acquired drug resistance in cancer. The high rate of epigenetic change in tumours …
of acquired drug resistance in cancer. The high rate of epigenetic change in tumours …
[HTML][HTML] Review of processing and analysis methods for DNA methylation array data
CS Wilhelm-Benartzi, DC Koestler, MR Karagas… - British journal of …, 2013 - nature.com
The promise of epigenome-wide association studies and cancer-specific somatic DNA
methylation changes in improving our understanding of cancer, coupled with the decreasing cost …
methylation changes in improving our understanding of cancer, coupled with the decreasing cost …
In Utero Exposures, Infant Growth, and DNA Methylation of Repetitive Elements and Developmentally Related Genes in Human Placenta
CS Wilhelm-Benartzi, EA Houseman… - Environmental …, 2012 - ehp.niehs.nih.gov
Background: Fetal programming describes the theory linking environmental conditions during
embryonic and fetal development with risk of diseases later in life. Environmental insults in …
embryonic and fetal development with risk of diseases later in life. Environmental insults in …
Birthweight is associated with DNA promoter methylation of the glucocorticoid receptor in human placenta
…, MA Maccani, DC Koestler, C Wilhelm-Benartzi… - Epigenetics, 2011 - Taylor & Francis
Birthweight has been associated with a number of health outcomes throughout life. Crucial
to proper infant growth and development is the placenta, and alterations to placental gene …
to proper infant growth and development is the placenta, and alterations to placental gene …
A model to predict vaginal delivery in nulliparous women based on maternal characteristics and intrapartum ultrasound
TM Eggebø, C Wilhelm-Benartzi, WA Hassan… - American journal of …, 2015 - Elsevier
Objective Accurate prediction of whether a nulliparous woman will have a vaginal delivery
would be a major advance in obstetrics. The objective of the study was to develop such a …
would be a major advance in obstetrics. The objective of the study was to develop such a …
Platinum-based chemotherapy induces methylation changes in blood DNA associated with overall survival in patients with ovarian cancer
Purpose: DNA damage repair can lead to epigenetic changes. DNA mismatch repair
proteins bind to platinum DNA adducts and at sites of DNA damage can recruit the DNA …
proteins bind to platinum DNA adducts and at sites of DNA damage can recruit the DNA …
Radiological predictors of cytoreductive outcomes in patients with advanced ovarian cancer
J Borley, C Wilhelm‐Benartzi, J Yazbek… - … Journal of Obstetrics …, 2015 - Wiley Online Library
Objective To assess site of disease on preoperative computed tomography ( CT ) to predict
surgical debulking in patients with ovarian cancer. Design Two‐phase retrospective cohort …
surgical debulking in patients with ovarian cancer. Design Two‐phase retrospective cohort …