[HTML][HTML] The genome sequences of Arachis duranensis and Arachis ipaensis, the diploid ancestors of cultivated peanut

…, B Vidigal, B Abernathy, Y Chu, CE Niederhuth… - Nature …, 2016 - nature.com
Cultivated peanut (Arachis hypogaea) is an allotetraploid with closely related subgenomes
of a total size of ∼2.7 Gb. This makes the assembly of chromosomal pseudomolecules very …

[HTML][HTML] Widespread natural variation of DNA methylation within angiosperms

CE Niederhuth, AJ Bewick, L Ji, MS Alabady, KD Kim… - Genome biology, 2016 - Springer
Background DNA methylation is an important feature of plant epigenomes, involved in the
formation of heterochromatin and affecting gene expression. Extensive variation of DNA …

On the origin and evolutionary consequences of gene body DNA methylation

AJ Bewick, L Ji, CE Niederhuth… - Proceedings of the …, 2016 - National Acad Sciences
In plants, CG DNA methylation is prevalent in the transcribed regions of many constitutively
expressed genes (gene body methylation; gbM), but the origin and function of gbM remain …

Single-molecule sequencing and optical mapping yields an improved genome of woodland strawberry (Fragaria vesca) with chromosome-scale contiguity

…, M Colle, TJ Poorten, CM Wai, CE Niederhuth… - …, 2018 - academic.oup.com
Background Although draft genomes are available for most agronomically important plant
species, the majority are incomplete, highly fragmented, and often riddled with assembly and …

Putting DNA methylation in context: from genomes to gene expression in plants

CE Niederhuth, RJ Schmitz - Biochimica et Biophysica Acta (BBA)-Gene …, 2017 - Elsevier
Plant DNA methylation is its own language, interpreted by the cell to maintain silencing of
transposons, facilitate chromatin structure, and to ensure proper expression of some genes. …

[HTML][HTML] The evolution of CHROMOMETHYLASES and gene body DNA methylation in plants

AJ Bewick, CE Niederhuth, L Ji, NA Rohr, PT Griffin… - Genome biology, 2017 - Springer
Background The evolution of gene body methylation (gbM), its origins, and its functional
consequences are poorly understood. By pairing the largest collection of transcriptomes (>1000…

A comparative analysis of 5-azacytidine-and zebularine-induced DNA demethylation

PT Griffin, CE Niederhuth… - G3: Genes, Genomes …, 2016 - academic.oup.com
The nonmethylable cytosine analogs, 5-azacytidine and zebularine, are widely used to inhibit
DNA methyltransferase activity and reduce genomic DNA methylation. In this study, whole-…

[PDF][PDF] Covering your bases: inheritance of DNA methylation in plant genomes

CE Niederhuth, RJ Schmitz - Molecular plant, 2014 - cell.com
Cytosine methylation is an important base modification that is inherited across mitotic and
meiotic cell divisions in plant genomes. Heritable methylation variants can contribute to within-…

[HTML][HTML] Transcriptional profiling of the Arabidopsis abscission mutant hae hsl2by RNA-Seq

CE Niederhuth, OR Patharkar, JC Walker - BMC genomics, 2013 - Springer
Background Abscission is a mechanism by which plants shed entire organs in response to
both developmental and environmental signals. Arabidopsis thaliana, in which only the floral …

Replaying the evolutionary tape to investigate subgenome dominance in allopolyploid Brassica napus

KA Bird, CE Niederhuth, S Ou, M Gehan… - New …, 2021 - Wiley Online Library
Allopolyploidisation merges evolutionarily distinct parental genomes (subgenomes) into a
single nucleus. A frequent observation is that one subgenome is ‘dominant’ over the other …