A novel chromosome segregation mechanism during female meiosis
In a wide range of eukaryotes, chromosome segregation occurs through anaphase A, in which
chromosomes move toward stationary spindle poles, anaphase B, in which chromosomes …
chromosomes move toward stationary spindle poles, anaphase B, in which chromosomes …
Katanin maintains meiotic metaphase chromosome alignment and spindle structure in vivo and has multiple effects on microtubules in vitro
K McNally, E Berg, DB Cortes… - Molecular biology of …, 2014 - Am Soc Cell Biol
Assembly of Caenorhabditis elegans female meiotic spindles requires both MEI-1 and MEI-2
subunits of the microtubule-severing ATPase katanin. Strong loss-of-function mutants …
subunits of the microtubule-severing ATPase katanin. Strong loss-of-function mutants …
Cross-linkers both drive and brake cytoskeletal remodeling and furrowing in cytokinesis
CP Descovich, DB Cortes, S Ryan, J Nash… - Molecular Biology of …, 2018 - Am Soc Cell Biol
Cell shape changes such as cytokinesis are driven by the actomyosin contractile cytoskeleton.
The molecular rearrangements that bring about contractility in nonmuscle cells are …
The molecular rearrangements that bring about contractility in nonmuscle cells are …
Micron-scale supramolecular myosin arrays help mediate cytoskeletal assembly at mature adherens junctions
HC Yu-Kemp, RA Szymanski, DB Cortes… - Journal of Cell …, 2021 - rupress.org
… DB Cortes designed and implemented the modeling experiments, with input from AS
Maddox and M. Peifer. HC. Yu-Kemp, RA Szymanski, DB Cortes, and M. Peifer wrote the …
Maddox and M. Peifer. HC. Yu-Kemp, RA Szymanski, DB Cortes, and M. Peifer wrote the …
The asymmetry of female meiosis reduces the frequency of inheritance of unpaired chromosomes
10.7554/eLife.06056.001 Trisomy, the presence of a third copy of one chromosome, is
deleterious and results in inviable or defective progeny if passed through the germ line. Random …
deleterious and results in inviable or defective progeny if passed through the germ line. Random …
Unite to divide–how models and biological experimentation have come together to reveal mechanisms of cytokinesis
Cytokinesis is the fundamental and ancient cellular process by which one cell physically
divides into two. Cytokinesis in animal and fungal cells is achieved by contraction of an …
divides into two. Cytokinesis in animal and fungal cells is achieved by contraction of an …
Novel cytokinetic ring components drive negative feedback in cortical contractility
Actomyosin cortical contractility drives many cell shape changes including cytokinetic furrowing.
While positive regulation of contractility is well characterized, counterbalancing negative …
While positive regulation of contractility is well characterized, counterbalancing negative …
Dynactin-dependent cortical dynein and spherical spindle shape correlate temporally with meiotic spindle rotation in Caenorhabditis elegans
…, JR Flynn, KP McNally, DB Cortes… - Molecular biology of …, 2015 - Am Soc Cell Biol
… After acquiring data, the RAW files were converted to MGF files and searched using MASCOT
2.2 (Matrix Science, London, United Kingdom) against an in-house database consisting of …
2.2 (Matrix Science, London, United Kingdom) against an in-house database consisting of …
[PDF][PDF] Importance and function of microbial communities in aquaculture systems with no water exchange
The goal of this review is to analyze the importance of microbial communities in systems
with zero or no water exchange or also called Bioflc, this because in recent decades has …
with zero or no water exchange or also called Bioflc, this because in recent decades has …
Spherical spindle shape promotes perpendicular cortical orientation by preventing isometric cortical pulling on both spindle poles during C. elegans female meiosis
E Vargas, KP McNally, DB Cortes, MT Panzica… - …, 2019 - journals.biologists.com
Meiotic spindles are positioned perpendicular to the oocyte cortex to facilitate segregation
of chromosomes into a large egg and a tiny polar body. In C. elegans, spindles are initially …
of chromosomes into a large egg and a tiny polar body. In C. elegans, spindles are initially …