User profiles for D. E. Cook

David E Cook

- Verified email at ksu.edu - Cited by 2254

Daniel E. Cook

- Verified email at google.com - Cited by 2078

Duncan Cook

- Verified email at acu.edu.au - Cited by 1011

Understanding plant immunity as a surveillance system to detect invasion

DE Cook, CH Mesarich… - Annual review of …, 2015 - annualreviews.org
Various conceptual models to describe the plant immune system have been presented. The
most recent paradigm to gain wide acceptance in the field is often referred to as the zigzag …

Mind the gap; seven reasons to close fragmented genome assemblies

…, MF Seidl, X Shi-Kunne, DE Cook… - Fungal Genetics and …, 2016 - Elsevier
… However, long-read sequencing technologies are still relatively expensive and therefore
not yet routinely used for de novo genome sequencing. Consequently, eukaryotic genome …

[HTML][HTML] A draft human pangenome reference

…, PC Chang, S Cody, DE Cook, RM Cook-Deegan… - Nature, 2023 - nature.com
Here the Human Pangenome Reference Consortium presents a first draft of the human
pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of …

[HTML][HTML] Antibodies against endogenous retroviruses promote lung cancer immunotherapy

…, M Al Bakir, EL Lim, MS Hill, GA Wilson, DE Cook… - Nature, 2023 - nature.com
B cells are frequently found in the margins of solid tumours as organized follicles in ectopic
lymphoid organs called tertiary lymphoid structures (TLS) 1 , 2 . Although TLS have been …

Copy Number Variation of Multiple Genes at Rhg1 Mediates Nematode Resistance in Soybean

DE Cook, TG Lee, X Guo, S Melito, K Wang… - science, 2012 - science.org
The rhg1-b allele of soybean is widely used for resistance against soybean cyst nematode (SCN),
the most economically damaging pathogen of soybeans in the United States. Gene …

[HTML][HTML] The evolution of lung cancer and impact of subclonal selection in TRACERx

…, O Pich, TBK Watkins, C Naceur-Lombardelli, DE Cook… - Nature, 2023 - nature.com
Lung cancer is the leading cause of cancer-associated mortality worldwide 1 . Here we
analysed 1,644 tumour regions sampled at surgery or during follow-up from the first 421 patients …

Tracking early lung cancer metastatic dissemination in TRACERx using ctDNA

…, E Manzano, CT Hiley, N Carey, J Riley, DE Cook… - Nature, 2023 - nature.com
Circulating tumour DNA (ctDNA) can be used to detect and profile residual tumour cells
persisting after curative intent therapy 1 . The study of large patient cohorts incorporating …

[HTML][HTML] The evolution of non-small cell lung cancer metastases in TRACERx

…, T Karasaki, C Abbosh, CT Hiley, MS Hill, DE Cook… - Nature, 2023 - nature.com
Metastatic disease is responsible for the majority of cancer-related deaths 1 . We report the
longitudinal evolutionary analysis of 126 non-small cell lung cancer (NSCLC) tumours from …

[HTML][HTML] Genomic–transcriptomic evolution in lung cancer and metastasis

…, EL Lim, AM Al-Rashed, D Lang, J Clements, DE Cook… - Nature, 2023 - nature.com
Intratumour heterogeneity (ITH) fuels lung cancer evolution, which leads to immune evasion
and resistance to therapy 1 . Here, using paired whole-exome and RNA sequencing data, …

CeNDR, the Caenorhabditis elegans natural diversity resource

DE Cook, S Zdraljevic, JP Roberts… - Nucleic acids …, 2017 - academic.oup.com
Studies in model organisms have yielded considerable insights into the etiology of disease
and our understanding of evolutionary processes. Caenorhabditis elegans is among the …