Background Sleep-disordered breathing is a common condition associated with adverse
health outcomes including hypertension and cardiovascular disease. The overall objective of …

The Sleep Heart Health Study (SHHS) is a prospective cohort study designed to investigate
obstructive sleep apnea (OSA) and other sleep-disordered breathing (SDB) as risk factors …

Disclaimer: ACMG standards and guidelines are designed primarily as an educational
resource for physicians and other health care providers to help them provide quality medical …

OBJECTIVE: To confirm the efficacy and safety of recombinant human α-L-iduronidase (laronidase)
in patients with mucopolysaccharidosis I (MPS I). STUDY DESIGN: This was a …

Rationale: Cross-sectional epidemiologic studies show an association between sleep-disordered
breathing and hypertension, but only one cohort study has examined sleep-disordered …

Disordered breathing during sleep is more common among postmenopausal women than
among their premenopausal counterparts, possibly because of declining levels of estrogen …

… Rapoport holds multiple US and foreign patents covering techniques and analysis algorithms
for the diagnosis of OSAHS and techniques for administering CPAP. Several of these have …

OBJECTIVE. Our goal was to evaluate the long-term safety and efficacy of recombinant
human α-l-iduronidase (laronidase) in patients with mucopolysaccharidosis I. PATIENTS AND …

The upper airway is the primary conduit for passage of air into the lungs. Its physiology has
been the subject of intensive study: both passive mechanical and active neural influences …

We previously showed that upper airway resistance can be inferred from the inspiratory flow
contour during continuous positive airway pressure (CPAP) titration in obstructive sleep …