A vast array of successive epigenetic modifications ensures the creation of a healthy individual.
Crucial epigenetic reprogramming events occur during germ cell development and early …

Embryo implantation involves the intimate interaction between an implantation-competent
blastocyst and a receptive uterus, which occurs in a limited time period known as the window …

The preimplantation embryo floats freely within the oviduct and is capable of developing into
a blastocyst independently of the maternal reproductive tract. While establishment of the …

OBJECTIVE: Toll-like receptors (TLRs) recognize microbial ligands and host products that
are released during tissue damage, the so-called “danger signals.” This study was conducted …

… We are also grateful to Dr. Michael McMaster for the 4H84 monoclonal antibody and Drs.
Yan Zhou and Caroline Damsky who provided the 7D3 monoclonal antibody, all from the …

… *Address all correspondence and requests for reprints to: Dr. DR Armant, Department of
Obstetrics and Gynecology, CS Mott Center for Human Growth and Development, Wayne State …

… Laminin used in this study was obtained from Dr. RB Runyan, Department of Biochemistry
and … A highly purified preparation of human plasma fibronectin was a generous gift from Dr. LB …

In vitro fertilization has provided a unique window into the metabolic processes that drive
embryonic growth and development from a fertilized ovum to a competent blastocyst. Post-…

Cytotrophoblasts of the anchoring villi convert during human placentation from a transporting
epithelium to an invasive, extravillous phenotype that expresses a distinct repertoire of …

The limited ability to vascularize and perfuse thick, cell-laden tissue constructs has hindered
efforts to engineer complex tissues and organs, including liver, heart and kidney. The …