Faithful duplication of the genome is a challenge because DNA is susceptible to damage by
a number of intrinsic and extrinsic genotoxins, such as free radicals and UV light. Cells …

Aneuploidy, a state of karyotype imbalance, is a hallmark of cancer. Changes in chromosome
copy number have been proposed to drive disease by modulating the dosage of cancer …

Peanut, found to be relatively drought tolerant crop, has been the choice of study to
characterize the genes expressed under gradual water deficit stress. Nearly 700 genes were …

Chromosome instability (CIN) is the most common form of genome instability and is a hallmark
of cancer. CIN invariably leads to aneuploidy, a state of karyotype imbalance. Here, we …

Chromogranin A (CHGA), a member of the granin family of proteins, has been an attractive
therapeutic target and candidate biomarker for several cardiovascular, neurological, and …

In response to DNA damage during S phase, cells slow DNA replication. This slowing is
orchestrated by the intra-S checkpoint and involves inhibition of origin firing and reduction of …

Cell cycle regulators are increasingly implicated in cell fate decisions, such as the acquisition
or loss of pluripotency and self-renewal potential. The cell cycle mechanisms that regulate …

… (A) Graph showing the percentage of GFP-positive cells after DR-GFP analysis. U2OS cells
were infected with I-SceI adenovirus and knocked down for BRCA1 or CHAMP1 using siRNA…

The procedure for repair welding of cracked steam turbine blades made of martensitic
stainless steels has been developed using the gas tungsten arc welding process. Weld repair …

… Assessment of gene conversion by DR-GFP assay. Effect of CCAR2 … DR-GFP assay was
performed as described previously (42). U2OS DR-GFP cells were a kind gift from Dr. Jeremy …