User profiles for D. Beule

Dieter Beule

Berlin Institute of Health, Charité
Verified email at bih-charite.de
Cited by 3962

The Treatment of Aspergillosis and Aspergilloma with Itraconazole, Clinical Results of an Open International Study (1982‐1987)/Die Behandlung der Aspergillose und …

K De Beule, P De Doncker, G Cauwenbergh… - Mycoses, 1988 - Wiley Online Library
A total of 137 patients with aspergillosis or aspergilloma has been treated with 50 to 400 mg
itraconazole daily during 11 to 780 days. The global assessments »markedly improved« …

[PDF][PDF] Transcriptional and translational differences of microglia from male and female brains

…, LS Artiles, B Kaminska, P Mertins, D Beule… - Cell reports, 2018 - cell.com
D) ATP-induced membrane currents were recorded while clamping the membrane every
5 s to a series of de… ) as indicated in the recording in (D). No significant differences in the …

Tumour ischaemia by interferon-γ resembles physiological blood vessel regression

…, W Uckert, N Hübner, H Gerhardt, D Beule… - Nature, 2017 - nature.com
… g–i, No effect as in d–f in control PIG ΔIFNγR mice. Scale bars, 0.5 cm (d, g). i, Dox at a …
The de novo synthesized sequences (IFNγ–GFP: 1,230 bp, TNF–GFP: 1,470 bp) contained NotI …

Extrachromosomal circular DNA drives oncogenic genome remodeling in neuroblastoma

…, P Hundsdoerfer, C Rosswog, J Theissen, D Beule… - Nature …, 2020 - nature.com
De novo sequence assembly of long reads spanning the entirety of circles allowed further
physical confirmation of their circular structure in 65% of cases (Supplementary Fig. 4a–c). …

[HTML][HTML] Maternal immune activation results in complex microglial transcriptome signature in the adult offspring that is reversed by minocycline treatment

…, BJL Eggen, E Boddeke, B Kaminska, D Beule… - Translational …, 2017 - nature.com
Maternal immune activation (MIA) during pregnancy has been linked to an increased risk of
developing psychiatric pathologies in later life. This link may be bridged by a defective …

Normalization strategies for cDNA microarrays

J Schuchhardt, D Beule, A Malik, E Wolski… - Nucleic Acids …, 2000 - academic.oup.com
… Comparing the four normalization schemes proposed, for our experiment the average pin-wise
strategy (D) seems most appropriate. Training and test performance are persistently …

Biological profiling of gene groups utilizing Gene Ontology

…, K Brand, B Cajavec, M Swat, H Herzel, D Beule - Genome …, 2005 - jstage.jst.go.jp
… However, the determination of statistical significance of a biological process within these …
, MM, Brown, PO, and Botstein, D., Identification of genes periodically expressed in the human …

Non-redundant functions of group 2 innate lymphoid cells

…, FR Heinrich, GM Guerra, P Durek, A Ivanov, D Beule… - Nature, 2022 - nature.com
d, Pearson correlation and linear regression of ILC2 and eosinophil frequencies. e, Eosinophil
lineage-committed progenitor (EoP) gated from live CD45 + Lin − (CD3, CD5, CD19, Gr1, …

[HTML][HTML] Increased risk of severe clinical course of COVID-19 in carriers of HLA-C* 04: 01

…, T Borodina, S Ripke, LE Sander, D Beule… - …, 2021 - thelancet.com
Background Since the beginning of the coronavirus disease 2019 (COVID-19) pandemic,
there has been increasing urgency to identify pathophysiological characteristics leading to …

[PDF][PDF] Complement activation induces excessive T cell cytotoxicity in severe COVID-19

…, MA Mall, S Stricker, J Röhmel, VM Corman, D Beule… - Cell, 2022 - cell.com
Severe COVID-19 is linked to both dysfunctional immune response and unrestrained
immunopathology, and it remains unclear whether T cells contribute to disease pathology. Here, …