… This hypothesis is analogous to the concept of focal disconnection syndromes put forth
40 years ago by Norman Geschwind, in which disruptions in connectivity between higher …

… Alarcon, M., Cantor, RM, Liu, J., Gilliam, TC & Geschwind, DH Evidence for a language …
Chen, GK, Kono, N., Geschwind, DH & Cantor, RM Quantitative trait locus analysis of nonverbal …

INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

Several families have been reported with autosomal-dominant frontotemporal dementia (FTD)
and amyotrophic lateral sclerosis (ALS), genetically linked to chromosome 9p21. Here, we …

We tested the hypothesis that de novo copy number variation (CNV) is associated with autism
spectrum disorders (ASDs). We performed comparative genomic hybridization (CGH) on …

Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …

Neuroanatomically precise, genome-wide maps of transcript distributions are critical resources
to complement genomic sequence data and to correlate functional and genetic brain …

We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n
= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …

The Alzheimer Disease Genetics Consortium (ADGC) performed a genome-wide association
study of late-onset Alzheimer disease using a three-stage design consisting of a discovery …

Multiple studies have confirmed the contribution of rare de novo copy number variations to
the risk for autism spectrum disorders 1 , 2 , 3 . But whereas de novo single nucleotide …