Rationale: Air pollution is a known asthma trigger and has been associated with short-term
asthma symptoms, airway inflammation, decreased lung function, and reduced response to …

Rationale: Obesity is associated with increased asthma morbidity, lower drug responsiveness
to inhaled corticosteroids, and worse asthma control. However, most prior investigations …

Background Childhood asthma prevalence and morbidity varies among Latinos in the
United States, with Puerto Ricans having the highest and Mexicans the lowest. Objective To …

Background Asthma is a complex disease with both genetic and environmental causes.
Genome-wide association studies of asthma have mostly involved European populations, and …

Rationale: The burden of asthma is highest among socioeconomically disadvantaged
populations; however, its impact is differentially distributed among racial and ethnic groups. …

10.7554/eLife.20532.001 Populations are often divided categorically into distinct racial/ethnic
groups based on social rather than biological constructs. Genetic ancestry has been …

Rationale: Adverse effects of exposures to ambient air pollution on lung function are well
documented, but evidence in racial/ethnic minority children is lacking. Objectives: To assess …

BACKGROUND: Among patients with asthma, the clinical effect and relative contribution of
maternal smoking during pregnancy (in utero smoking) and current secondhand smoke (SHS…

Background IgE is a key mediator of allergic inflammation, and its levels are frequently
increased in patients with allergic disorders. Objective We sought to identify genetic variants …

Background Secondhand smoke (SHS) exposures have been linked to asthma-related
outcomes but quantitative dose–responses using biomarkers of exposure have not been widely …