Purpose: We determine the contrast-to-noise ratios (CNRs) of structural and functional
measurements to assess their sensitivity to detect progression in the various stages of glaucoma. …

Purpose: To determine the sensitivity of optical coherence tomography (OCT) and standard
automated perimetry (SAP) for detecting glaucomatous progression in the superior and …

… duration +30 ms, mean Ea >10.0 cm/s, and E/Ea <9. Stage 1 … 0.75 and 1.5, with a mean Ea
<7 cm/s and E/Ea >15. Stage 3 … time <150 ms, mean Ea <7 cm/s, and E/Ea >15 reversing to …

A cross-sectional study in a cohort of DNA proven carriers of Duchenne (DMD) and Becker (BMD)
muscular dystrophy was undertaken with the following objectives: (1) to estimate the …

Identifying subjects with cystic fibrosis (CF) who may benefit from cystic fibrosis transmembrane
conductance regulator (CFTR)–modulating drugs is time-consuming, costly, and …

In vitro drug tests using patient-derived stem cell cultures offer opportunities to individually
select efficacious treatments. Here, we provide a study that demonstrates that in vitro drug …

Background Recently, endogenous glucocorticoid excess has been identified as a risk factor
for VTE. Whether exogenous use of glucocorticoids is associated with an increased risk of …

Conflict lies at the core of urban sustainability transitions and the indispensable structural
changes that accompany them. In this chapter we examine the RESILIO project, a multi-actor …

Some of the most damaging tree pathogens can attack woody stems, causing lesions (cankers)
that may be lethal. To identify the genomic determinants of wood colonization leading to …

In this part of a series on cardiogenetic founder mutations in the Netherlands, we review the
Dutch founder mutations in hypertrophic cardiomyopathy (HCM) patients. HCM is a common …