Clinical evidence suggests that nano- and microtopography incorporated into scaffolds
does not merely improve peripheral nerve regeneration, but is in fact a prerequisite for …

Multiphoton lithography (MPL) is a highly versatile strategy for creating 3D microscale objects
with complex geometrical arrangements, including nested boxes, interlocking blocks, and …

A transmission geometry optical configuration allows for smaller laser spot size to facilitate
high‐resolution matrix‐assisted laser/desorption ionization (MALDI) mass spectrometry. This …

Due to their short lifespan, rapid division, and ease of genetic manipulation, yeasts are popular
model organisms for studying aging in actively dividing cells. To study replicative aging …

10.7554/eLife.32948.001 The heterochromatin spreading reaction is a central contributor to
the formation of gene-repressive structures, which are re-established with high positional …

10.7554/eLife.20340.001 The replicative lifespan (RLS) of a cell—defined as the number of
cell divisions before death—has informed our understanding of the mechanisms of cellular …

Human microphysiological systems, such as organs on chips, are an emerging technology
for modeling human physiology in a preclinical setting to understand the mechanism of action …

… During his graduate studies, Dr Spivey developed long scan μ3D-printing, a multiphoton
laser-based micro-fabrication technique. More recently, he has used his background in …

Activation of mitogen-activated protein kinases (MAPKs) was examined in the A7r5 rat
vascular smooth muscle cell line. Treatment of A7r5 cells with vasopressin, phorbol ester (PMA), …

Phospholipase D (PLD) is activated in mammalian cells in response to a wide variety of stimuli.
A rapid assay for agonist-activated PLD activity in cell extracts was developed, utilizing a …