User profiles for E. W. van Zwet

Erik van Zwet

Associate Professor, Leiden University Medical Center
Verified email at lumc.nl
Cited by 12169

The apparent paradox of maternal seropositivity as a risk factor for congenital cytomegalovirus infection: a population‐based prediction model

JJC de Vries, EW van Zwet, FW Dekker… - Reviews in medical …, 2013 - Wiley Online Library
Because maternal seropositivity for CMV is associated with substantial protection against
congenital CMV infection, prevention measures have focused mainly on seronegative …

[HTML][HTML] DNA methylation signatures link prenatal famine exposure to growth and metabolism

…, AP Stok, PE Thijssen, F Müller, EW Van Zwet… - Nature …, 2014 - nature.com
Periconceptional diet may persistently influence DNA methylation levels with phenotypic
consequences. However, a comprehensive assessment of the characteristics of prenatal …

Disease variants alter transcription factor levels and methylation of their binding sites

…, CG Schalkwijk, LH Van Den Berg, EW Van Zwet… - Nature …, 2017 - nature.com
Most disease-associated genetic variants are noncoding, making it challenging to design
experiments to understand their functional consequences 1 , 2 . Identification of expression …

Cerebral injury in monochorionic twins with selective intrauterine growth restriction: a systematic review

…, JMM van Klink, TT Stolk, EW van Zwet… - Prenatal …, 2014 - Wiley Online Library
Objective To estimate incidence and risk factors of severe cerebral injury in survivors from
monochorionic pregnancies with selective intrauterine growth restriction (sIUGR) and/or birth …

Fetoscopic laser coagulation of the vascular equator versus selective coagulation for twin-to-twin transfusion syndrome: an open-label randomised controlled trial

…, E Lopriore, L Lewi, JM Middeldorp, EW Van Zwet… - The Lancet, 2014 - thelancet.com
Background Monochorionic twin pregnancies complicated by twin-to-twin transfusion syndrome
are typically treated with fetoscopic laser coagulation. Postoperative complications can …

[HTML][HTML] Hysterectomy in very obese and morbidly obese patients: a systematic review with cumulative analysis of comparative studies

MD Blikkendaal, EM Schepers, EW van Zwet… - Archives of gynecology …, 2015 - Springer
Purpose Some studies suggest that also regarding the patient with a body mass index (BMI)
≥35 kg/m 2 the minimally invasive approach to hysterectomy is superior. However, current …

DNA methylation as a mediator of the association between prenatal adversity and risk factors for metabolic disease in adulthood

…, PE Slagboom, EW van Zwet… - Science …, 2018 - science.org
Although it is assumed that epigenetic mechanisms, such as changes in DNA methylation (DNAm),
underlie the relationship between adverse intrauterine conditions and adult …

[HTML][HTML] Controlling bias and inflation in epigenome-and transcriptome-wide association studies using the empirical null distribution

M van Iterson, EW van Zwet, Bios Consortium… - Genome biology, 2017 - Springer
We show that epigenome- and transcriptome-wide association studies (EWAS and TWAS)
are prone to significant inflation and bias of test statistics, an unrecognized phenomenon …

Cutaneous allodynia as a predictor of migraine chronification

…, JE Bosker, WPJ Van Oosterhout, EW Van Zwet… - Brain, 2013 - academic.oup.com
Cutaneous allodynia is a common feature accompanying migraine attacks and considered
a clinical marker for central sensitization. In a longitudinal study, we wanted to investigate if …

Endosonography vs conventional bronchoscopy for the diagnosis of sarcoidosis: the GRANULOMA randomized clinical trial

…, C Porsbjerg, T Mauad, FD Bernardi, EW van Zwet… - Jama, 2013 - jamanetwork.com
Importance Tissue verification of noncaseating granulomas is recommended for the diagnosis
of sarcoidosis. Bronchoscopy with transbronchial lung biopsies, the current diagnostic …