The mitotic spindle: a self-made machine

E Karsenti, I Vernos - Science, 2001 - science.org
The mitotic spindle is a highly dynamic molecular machine composed of tubulin, motors,
and other molecules. It assembles around the chromosomes and distributes the duplicated …

Self-organization in cell biology: a brief history

E Karsenti - Nature reviews Molecular cell biology, 2008 - nature.com
Over the past two decades, molecular and cell biologists have made important progress in
characterizing the components and compartments of the cell. New visualization methods …

Tara Oceans: towards global ocean ecosystems biology

…, G Gorsky, L Guidi, D Iudicone, E Karsenti… - Nature Reviews …, 2020 - nature.com
A planetary-scale understanding of the ocean ecosystem, particularly in light of climate
change, is crucial. Here, we review the work of Tara Oceans, an international, multidisciplinary …

Structure and function of the global ocean microbiome

…, E Karsenti, J Raes, SG Acinas, P Bork, E Boss… - Science, 2015 - science.org
Microbes are dominant drivers of biogeochemical processes, yet drawing a global picture of
functional diversity, microbial community structure, and their ecological determinants …

Eukaryotic plankton diversity in the sunlit ocean

…, J Weissenbach, P Wincker, E Karsenti, E Boss… - Science, 2015 - science.org
Marine plankton support global biological and geochemical processes. Surveys of their
biodiversity have hitherto been geographically restricted and have not accounted for the full …

Self-organization of microtubules into bipolar spindles around artificial chromosomes in Xenopus egg extracts

…, R Sandaltzopoulos, P Becker, A Hyman, E Karsenti - Nature, 1996 - nature.com
Functional nuclei and mitotic spindles are shown to assemble around DNA-coated beads
incubated in Xenopus egg extracts. Bipolar spindles assemble in the absence of centrosomes …

Determinants of community structure in the global plankton interactome

…, S Sunagawa, P Bork, MB Sullivan, E Karsenti… - Science, 2015 - science.org
Species interaction networks are shaped by abiotic and biotic factors. Here, as part of the
Tara Oceans project, we studied the photic zone interactome using environmental factors and …

[HTML][HTML] Ran induces spindle assembly by reversing the inhibitory effect of importin α on TPX2 activity

…, J Kast, M Wilm, N Le Bot, I Vernos, E Karsenti… - Cell, 2001 - cell.com
The small GTPase Ran, bound to GTP, is required for the induction of spindle formation by
chromosomes in M phase. High concentrations of Ran.GTP are proposed to surround M …

Plankton networks driving carbon export in the oligotrophic ocean

…, D Iudicone, MB Sullivan, J Raes, E Karsenti… - Nature, 2016 - nature.com
The biological carbon pump is the process by which CO 2 is transformed to organic carbon
via photosynthesis, exported through sinking particles, and finally sequestered in the deep …

Phosphorylation and activation of human cdc25‐C by cdc2‐‐cyclin B and its involvement in the self‐amplification of MPF at mitosis.

I Hoffmann, PR Clarke, MJ Marcote, E Karsenti… - The EMBO …, 1993 - embopress.org
… Draetta and E.Karsenti, in preparation). We assessed the ability of exogenous cdc25-C to
activate the cdc2-cyclin Bi complex in these extracts by measuring the cdc2 histone HI kinase …