Active chromatin and transcription play a key role in chromosome partitioning into topologically associating domains

…, AA Gavrilov, IM Flyamer, P Kos, EA Mikhaleva… - Genome …, 2016 - genome.cshlp.org
Recent advances enabled by the Hi-C technique have unraveled many principles of chromosomal
folding that were subsequently linked to disease and gene regulation. In particular, Hi-…

Separation of stem cell maintenance and transposon silencing functions of Piwi protein

…, AD Stolyarenko, EA Mikhaleva… - Proceedings of the …, 2011 - National Acad Sciences
… Previously, we have shown that the spn-E mutation leads to the opening of
retrotransposon chromatin structure in the ovaries (36). As Piwi is a single Drosophila piRNA-interacting …

[HTML][HTML] Nuclear lamina integrity is required for proper spatial organization of chromatin in Drosophila

…, AA Ilyin, IM Flyamer, EA Mikhaleva… - Nature …, 2019 - nature.com
How the nuclear lamina (NL) impacts on global chromatin architecture is poorly understood.
Here, we show that NL disruption in Drosophila S2 cells leads to chromatin compaction and …

[HTML][HTML] Order and stochasticity in the folding of individual Drosophila genomes

…, KE Polovnikov, IM Flyamer, EA Mikhaleva… - Nature …, 2021 - nature.com
Mammalian and Drosophila genomes are partitioned into topologically associating domains
(TADs). Although this partitioning has been reported to be functionally relevant, it is unclear …

Caloric characteristics of PbTiO3 in the temperature range of the ferroelectric phase transition

EA Mikhaleva, IN Flerov, MV Gorev… - Physics of the Solid …, 2012 - Springer
… The analysis of the electrical equation of state –E = 2AT(T – Tc)P + 4BP3 + 6CP5 made it
possible to con struct the thermodynamic surface P–E–T of the PbTiO3 ferroelectric (Fig. 5). …

[HTML][HTML] Role of histone deacetylases in gene regulation at nuclear lamina

…, SA Lavrov, VV Nenasheva, EA Mikhaleva… - PloS one, 2012 - journals.plos.org
Theoretical models suggest that gene silencing at the nuclear periphery may involve “closing”
of chromatin by transcriptional repressors, such as histone deacetylases (HDACs). Here …

Piwi interacts with chromatin at nuclear pores and promiscuously binds nuclear transcripts in Drosophila ovarian somatic cells

…, SA Doronin, OM Olenkina, EA Mikhaleva… - Nucleic acids …, 2017 - academic.oup.com
… All the terms with the evidence codes inferred from electronic annotation, inferred from
reviewed computational analysis or no biological data available were removed before the analysis…

[HTML][HTML] The large fraction of heterochromatin in Drosophila neurons is bound by both B-type lamin and HP1a

…, MV Tselebrovsky, VV Nenasheva, EA Mikhaleva… - Epigenetics & …, 2018 - Springer
Background In most mammalian cell lines, chromatin located at the nuclear periphery is
represented by condensed heterochromatin, as evidenced by microscopy observations and …

Challenges and prospects of the legal regulation of robotics

ES Mikhaleva, EA Shubina - Actual problems of Russian law, 2020 - aprp.msal.ru
The modern world almost continuously emphasizes the importance of new challenges and
solutions in all areas and fields of life for humanity. The emergence of new technologies and …

Caloric and multicaloric effects in oxygen ferroics and multiferroics

IN Flerov, EA Mikhaleva, MV Gorev… - Physics of the Solid …, 2015 - Springer
… tics), a special place is occupied by caloric effects (CE) associated with a reversible change
in the entropy and temperature of the system in response to external fields (electric field E, …