Large language models (LLMs) have been shown to be able to perform new tasks based on
a few demonstrations or natural language instructions. While these capabilities have led to …

… Author links open overlay panel Eviatar Natan 1 , Jonathan N Wells 2 , Sarah A
Teichmann 3 , Joseph A Marsh 2 … ED Levy, E. Boeri Erba, CV Robinson, SA Teichmann …

Oligomerization of members of the p53 family of transcription factors (p53, p63, and p73) is
essential for their distinct functions in cell-cycle control and development. To elucidate the …

… (electronic supplementary material, table S2) and five examples are shown in figure 3a–e. …
with all human-derived samples (figure 3e). These preliminary findings suggest two things: (i…

The tetrameric tumor suppressor p53 plays a pivotal role in the control of the cell cycle and
provides a paradigm for an emerging class of oligomeric, multidomain proteins with …

… It is thus not surprising that a p53 dimer does not bind a quarter-site RE (E. Natan and AR
Fersh, unpublished work) and there are no known quarter-site REs (→). This range of REs, …

… We expressed site-specifically acetylated p53 in E. coli cells by genetically encoding the
incorporation of N ε -acetyl-lysine in response to the amber stop codon. The quadruple-mutant …

The use of ion mobility mass spectrometry (IM-MS) to study the topology of proteins and their
complexes is attracting considerable attention.[1] Under the appropriate conditions results …

The transcription factor Rora has been shown to be important for the development of ILC2
and the regulation of ILC3, macrophages and Treg cells. Here we investigate the role of Rora …

… We found a significant number of E. coli homomeric complexes interacting with chaperones,
but no significant difference was detected between homomeric and heteromeric complexes (…