[HTML][HTML] Falls in young, middle-aged and older community dwelling adults: perceived cause, environmental factors and injury
LA Talbot, RJ Musiol, EK Witham, EJ Metter - BMC public health, 2005 - Springer
Background Falls in older people have been characterized extensively in the literature,
however little has been reported regarding falls in middle-aged and younger adults. The …
however little has been reported regarding falls in middle-aged and younger adults. The …
[HTML][HTML] A tachykinin-like neuroendocrine signalling axis couples central serotonin action and nutrient sensing with peripheral lipid metabolism
L Palamiuc, T Noble, E Witham, H Ratanpal… - Nature …, 2017 - nature.com
… (e) Individual values for the fluorescence intensity of CLM::GFP within a single coelomocyte
are shown for each condition. Bars indicate the average value±sem within each condition. …
are shown for each condition. Bars indicate the average value±sem within each condition. …
Cardiac-restricted angiotensin-converting enzyme overexpression causes conduction defects and connexin dysregulation
…, S Iravanian, J Langberg, EA Witham… - American Journal …, 2007 - journals.physiology.org
Renin-angiotensin (RAS) system activation is associated with an increased risk of sudden
death. Previously, we used cardiac-restricted angiotensin-converting enzyme (ACE) …
death. Previously, we used cardiac-restricted angiotensin-converting enzyme (ACE) …
Prenatal exposure to low levels of androgen accelerates female puberty onset and reproductive senescence in mice
EA Witham, JD Meadows, S Shojaei… - …, 2012 - academic.oup.com
… In females, the ovaries produce testosterone (T), which is aromatized by follicle-derived
aromatase into estradiol (E 2 ) (1). E 2 and T exert feedback effects (E 2 , positive and negative; T…
aromatase into estradiol (E 2 ) (1). E 2 and T exert feedback effects (E 2 , positive and negative; T…
Kisspeptin regulates gonadotropin genes via immediate early gene induction in pituitary gonadotropes
EA Witham, JD Meadows, HM Hoffmann… - Molecular …, 2013 - academic.oup.com
… Our finding that pituitary Kiss1r was increased during the LH surge in OVX+E females
provides a physiologic context for furthering the understanding of kisspeptin's role in the pituitary. …
provides a physiologic context for furthering the understanding of kisspeptin's role in the pituitary. …
[PDF][PDF] C. elegans body cavity neurons are homeostatic sensors that integrate fluctuations in oxygen availability and internal nutrient reserves
E Witham, C Comunian, H Ratanpal, S Skora… - Cell reports, 2016 - cell.com
… (E) Fluorescent image of a transgenic animal bearing a gpa-8::GFP transgene. Blue
arrowheads indicate expression in AQR and PQR neurons, and the white arrowhead indicates …
arrowheads indicate expression in AQR and PQR neurons, and the white arrowhead indicates …
Inhibition of renin-angiotensin system (RAS) reduces ventricular tachycardia risk by altering connexin43
…, E Dolmatova, Z Jiao, BS Harris, EA Witham… - Journal of Molecular …, 2011 - Springer
Renin-angiotensin system (RAS) activation is associated with arrhythmias. We investigated
the effects of RAS inhibition in cardiac-specific angiotensin-converting enzyme (ACE) …
the effects of RAS inhibition in cardiac-specific angiotensin-converting enzyme (ACE) …
[PDF][PDF] NACHO engages N-glycosylation ER chaperone pathways for α7 nicotinic receptor assembly
The α7 nicotinic acetylcholine receptor participates in diverse aspects of brain physiology and
disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic …
disease. Neurons tightly control α7 assembly, which relies upon NACHO, an endoplasmic …
[HTML][HTML] Oxygen-sensing neurons reciprocally regulate peripheral lipid metabolism via neuropeptide signaling in Caenorhabditis elegans
R Hussey, NK Littlejohn, E Witham, E Vanstrum… - PLoS …, 2018 - journals.plos.org
The mechanisms by which the sensory environment influences metabolic homeostasis remains
poorly understood. In this report, we show that oxygen, a potent environmental signal, is …
poorly understood. In this report, we show that oxygen, a potent environmental signal, is …
Msx1 homeodomain protein represses the αGSU and GnRH receptor genes during gonadotrope development
…, JD Meadows, EA Witham… - Molecular …, 2013 - academic.oup.com
… After closure of Rathke's pouch on embryonic day (e)12 in the mouse, 5 endocrine cell types
arise in a specific spatial and temporal pattern giving rise to the anterior pituitary (1, 2). The …
arise in a specific spatial and temporal pattern giving rise to the anterior pituitary (1, 2). The …