Enhancer regions and transcription start sites of estrogen-target regulated genes are connected
by means of Estrogen Receptor long-range chromatin interactions. Yet, the complete …

Genome-wide association studies have identified numerous loci linked to breast cancer
susceptibility, but the mechanism by which variations at these loci influence susceptibility is …

Recently, FGFR1 was found to be overexpressed in osteosarcoma and represents an
important target for precision medicine. However, because targeted cancer therapy based on …

La intención de este artículo es desplegar una forma de interrogar a una técnica de recolección
de información a través del análisis del proceso de interacción de las reflexividades …

Estrogen receptor (ER) is a hormone-regulated transcription factor that controls cell division
and differentiation in the ovary, breast, and uterus. The expression of ER is a common …

p130Cas adaptor protein regulates basic processes such as cell cycle control, survival and
migration. p130Cas over-expression has been related to mammary gland transformation, …

Estrogen Receptor (ER) is a nuclear receptor that mediates the actions of estrogen and
tamoxifen. ER is expressed in a major fraction of human breast cancers. Recently, genomic …

There is an unmet medical need for new therapeutic approaches and targets for patients with
non-Hodgkin lymphoma (NHL) who relapse or are refractory to anti-CD20 immunotherapy. …

Background: CD37 is a tetraspanin protein abundant on the surface of B-cells but absent in
hematopoietic stem cells and plasma cells. Its expression pattern has attracted interest as a …

Background Rhabdomyosarcoma (RMS) is a paediatric cancer driven either by fusion
proteins (eg, PAX3-FOXO1) or by mutations in key signalling molecules (eg, RAS or FGFR4). …