Numerous studies have associated alterations in the gut microbiota composition with almost
every known inflammatory disease. However, proving the biological relevance of distinct …

Background Bacteria within family S24-7 (phylum Bacteroidetes) are dominant in the mouse
gut microbiota and detected in the intestine of other animals. Because they had not been …

Hepatocellular carcinoma (HCC) is a leading cause of cancer-related deaths worldwide,
and therapeutic options for advanced HCC are limited. Here, we observe that intestinal …

Prevotella spp. are a dominant bacterial genus within the human gut. Multiple Prevotella spp.
co-exist in some individuals, particularly those consuming plant-based diets. Additionally, …

Objective There is a striking association between human cholestatic liver disease (CLD) and
inflammatory bowel disease. However, the functional implications for intestinal microbiota …

Interleukin-17A– (IL-17A) and IL-17F–producing CD4 + T helper cells (T H 17 cells) are
implicated in the development of chronic inflammatory diseases, such as multiple sclerosis and …

Gut colonization with multidrug-resistant (MDR) bacteria enhances the risk of bloodstream
infections in susceptible individuals. We demonstrate highly variable degrees of ex vivo …

Inflammatory bowel disease comprises a group of heterogeneous diseases characterized
by chronic and relapsing mucosal inflammation. Alterations in microbiota composition have …

The microbiota contributes to colonization resistance against invading pathogens by
competing for metabolites, producing inhibitory substances, and priming protective immune …

Diverse microbial signatures within the intestinal microbiota have been associated with
intestinal and systemic inflammatory diseases, but whether these candidate microbes actively …