Proteolytic regulation of alginate overproduction in Pseudomonas aeruginosa

FH Damron, JB Goldberg - Molecular microbiology, 2012 - Wiley Online Library
… media such as l-agar (Damron and Yu, unpubl. obs.) or Pseudomonas isolation agar (PIA)
(… for the mucoid phenotype in strains with wild-type mucA (Damron and Yu, unpubl. obs.). …

PBAD-Based Shuttle Vectors for Functional Analysis of Toxic and Highly Regulated Genes in Pseudomonas and Burkholderia spp. and Other Bacteria

D Qiu, FH Damron, T Mima… - Applied and …, 2008 - Am Soc Microbiol
We report the construction of a series of Escherichia-Pseudomonas broad-host-range
expression vectors utilizing the P BAD promoter and the araC regulator for routine cloning, …

[HTML][HTML] Dual-seq transcriptomics reveals the battle for iron during Pseudomonas aeruginosa acute murine pneumonia

FH Damron, AG Oglesby-Sherrouse, A Wilks… - Scientific reports, 2016 - nature.com
Determining bacterial gene expression during infection is fundamental to understand
pathogenesis. In this study, we used dual RNA-seq to simultaneously measure P. aeruginosa and …

Overcoming waning immunity in pertussis vaccines: workshop of the National Institute of Allergy and Infectious Diseases

FH Damron, M Barbier, P Dubey… - The Journal of …, 2020 - journals.aai.org
Damron also mentioned that mRNA-based platform vaccines can also be used to produce
a more diverse response profile to a higher number of Ags than current acellular vaccines …

[HTML][HTML] Intranasal COVID-19 vaccine induces respiratory memory T cells and protects K18-hACE mice against SARS-CoV-2 infection

…, O Miller, M Cooper, SD Jazayeri, FH Damron… - npj Vaccines, 2023 - nature.com
Current COVID-19 vaccines prevent severe disease, but do not induce mucosal immunity or
prevent infection with SARS-CoV-2, especially with recent variants. Furthermore, serum …

[HTML][HTML] Intranasal administration of BReC-CoV-2 COVID-19 vaccine protects K18-hACE2 mice against lethal SARS-CoV-2 challenge

…, I Martinez, JR Bevere, RK Ernst, FH Damron - npj Vaccines, 2022 - nature.com
SARS-CoV-2 is a viral respiratory pathogen responsible for the current global pandemic
and the disease that causes COVID-19. All current WHO approved COVID-19 vaccines are …

Analysis of the Pseudomonas aeruginosa regulon controlled by the sensor kinase KinB and sigma factor RpoN

FH Damron, JP Owings, Y Okkotsu, JJ Varga… - Journal of …, 2012 - Am Soc Microbiol
Alginate overproduction by Pseudomonas aeruginosa , also known as mucoidy, is associated
with chronic endobronchial infections in cystic fibrosis. Alginate biosynthesis is initiated by …

The Pseudomonas aeruginosa Sensor Kinase KinB Negatively Controls Alginate Production through AlgW-Dependent MucA Proteolysis

FH Damron, D Qiu, HD Yu - Journal of bacteriology, 2009 - Am Soc Microbiol
Mucoidy, or overproduction of the exopolysaccharide known as alginate, in Pseudomonas
aeruginosa is a poor prognosticator for lung infections in cystic fibrosis. Mutation of the anti-σ …

[HTML][HTML] SARS-CoV-2 Delta variant induces enhanced pathology and inflammatory responses in K18-hACE2 mice

…, MS Amin, I Martinez, JR Bevere, FH Damron - Plos one, 2022 - journals.plos.org
The COVID-19 pandemic has been fueled by SARS-CoV-2 novel variants of concern (VOC)
that have increased transmissibility, receptor binding affinity, and other properties that …

The Pseudomonas aeruginosa PrrF small RNAs regulate iron homeostasis during acute murine lung infection

…, J Bevere, JW Jones, MA Kane, FH Damron… - Infection and …, 2017 - Am Soc Microbiol
Pseudomonas aeruginosa is a Gram-negative opportunistic pathogen that requires iron for
virulence. Iron homeostasis is maintained in part by the PrrF1 and PrrF2 small RNAs (sRNAs)…