… Frank Jan de Jong … Paulus TVM de Jong … Hofman A, Grobbee DE, de Jong PT, van den
Ouweland FA. Determinants of disease and disability in the elderly: the Rotterdam Elderly Study. …

Background: Retinal vessels may provide information on cerebral vascular pathology, because
they share many features with cerebral vessels. A smaller ratio of the retinal arteriolar-to-…

Introduction Cerebrospinal fluid collection by lumbar puncture (LP) is performed in the diagnostic
workup of several neurological brain diseases. Reluctance to perform the procedure is …

… Paulus TVM De Jong Paulus TVM De Jong … Bots ML, Hofman A, De Jong PT, Grobbee DE.
Common carotid intima-media thickness as an indicator of atherosclerosis at other sites of the …

BACKGROUND: Subjective memory complaints are common in the elderly. Although memory
complaints are associated with an increased risk of Alzheimer’s disease in persons with …

The insular cortex is proposed to function as a central brain hub characterized by wide-spread
connections and diverse functional roles. As a result, its centrality in the brain confers high …

The genetic architecture of dementia with Lewy bodies (DLB) is increasingly taking shape.
Initially, genetic research focused mainly on linkage and candidate gene studies in small …

… PTVM de Jong reports no disclosures. Dr. Hofman has received funding for travel from
GlaxoSmithKline; serves as Editor-in-Chief for the European Journal of Epidemiology; receives …

Background Most patients with Parkinson's disease, Parkinson's disease dementia, and
dementia with Lewy bodies do not carry mutations in known disease-causing genes. The aim of …

Background Neurofilament light chain (NfL) is a promising blood biomarker in genetic
frontotemporal dementia, with elevated concentrations in symptomatic carriers of mutations in GRN…