To date, pharmacological treatments for mood and anxiety disorders and for drug dependence
show limited efficacy, leaving a large number of patients suffering severe and persistent …

BackgroundItem 9 of the Patient Health Questionnaire-9 (PHQ-9) queries about thoughts of
death and self-harm, but not suicidality. Although it is sometimes used to assess suicide risk, …

Objective: To conduct a systematic literature review of animal and human studies reporting
anxiolytic or antidepressive effects of ayahuasca or some of its isolated alkaloids (…

BackgroundRecent open-label trials show that psychedelics, such as ayahuasca, hold
promise as fast-onset antidepressants in treatment-resistant depression.MethodsTo test the …

Objectives: Ayahuasca (AYA), a natural psychedelic brew prepared from Amazonian plants
and rich in dimethyltryptamine (DMT) and harmine, causes effects of subjective well-being …

Aim The Structured Clinical Interview for the DSM is one of the most used diagnostic
instruments in clinical research worldwide. The current Clinician Version of the instrument (SCID‐5‐…

… The primary studies by Osório et al. (2012) were funded by Reitoria de Pesquisa da
Universidade de São Paulo (grant number 09.1.01689.17.7) and Banco Santander (grant number …

The objective of this study was to propose an intervention and safety protocol for performing
animal-assisted therapy (AAT) and evaluating its efficacy in children under outpatient …

Serotonergic hallucinogens produce alterations of perceptions, mood, and cognition, and
have anxiolytic, antidepressant, and antiaddictive properties. These drugs act as agonists of …

Background: Screening for major depression with the Patient Health Questionnaire-9 (PHQ-9)
can be done using a cutoff or the PHQ-9 diagnostic algorithm. Many primary studies …