Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder
…, J Bybjerg-Grauholm, M Bækvad-Hansen, F Cerrato… - Nature …, 2019 - nature.com
Attention deficit/hyperactivity disorder (ADHD) is a highly heritable childhood behavioral
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
disorder affecting 5% of children and 2.5% of adults. Common genetic variants contribute …
Identification of common genetic risk variants for autism spectrum disorder
…, J Bybjerg-Grauholm, M Bækvad-Hansen, F Cerrato… - Nature …, 2019 - nature.com
Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic variants …
[PDF][PDF] Large-scale exome sequencing study implicates both developmental and functional changes in the neurobiology of autism
We present the largest exome sequencing study of autism spectrum disorder (ASD) to date (n
= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …
= 35,584 total samples, 11,986 with ASD). Using an enhanced analytical framework to …
Genome-wide association study identifies 30 loci associated with bipolar disorder
…, J Bybjerg-Grauholm, W Byerley, M Casas, F Cerrato… - Nature …, 2019 - nature.com
Bipolar disorder is a highly heritable psychiatric disorder. We performed a genome-wide
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
association study (GWAS) including 20,352 cases and 31,358 controls of European descent, …
[PDF][PDF] Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
…, CL Burton, J Bybjerg-Grauholm, M Casas, F Cerrato… - Cell, 2019 - cell.com
Genetic influences on psychiatric disorders transcend diagnostic boundaries, suggesting
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
substantial pleiotropy of contributing loci. However, the nature and mechanisms of these …
[HTML][HTML] Red grape juice polyphenols alter cholesterol homeostasis and increase LDL-receptor activity in human cells in vitro
A Davalos, C Fernández-Hernando, F Cerrato… - The Journal of …, 2006 - Elsevier
Red grape juice (RGJ) polyphenols have been shown to reduce circulating levels of LDL
cholesterol and to increase LDL receptor activity. To explore the effect of RGJ-derived …
cholesterol and to increase LDL receptor activity. To explore the effect of RGJ-derived …
Diagnosis and management of fibroadenomas in the adolescent breast
F Cerrato, BI Labow - Seminars in plastic surgery, 2013 - thieme-connect.com
Fibroadenomas are benign breast masses that can present a management challenge in
adolescent populations. Most fibroadenomas may be managed conservatively without surgery, …
adolescent populations. Most fibroadenomas may be managed conservatively without surgery, …
Kiss1 −/− Mice Exhibit More Variable Hypogonadism than Gpr54−/− Mice
…, D Zhang, YM Chan, A Mahan, F Cerrato… - …, 2007 - academic.oup.com
… C and F, PCR amplified a fragment of 453 bp in WT (+/+) mice, fragments of 453 and 1205
bp in heterozygous (+/−) mice, and a fragment of 1205 bp in Kiss1 mutant (−/−) mice (C) and a …
bp in heterozygous (+/−) mice, and a fragment of 1205 bp in Kiss1 mutant (−/−) mice (C) and a …
Phylogenetic analysis of SARS-CoV-2 in Boston highlights the impact of superspreading events
…, C Cusick, K Flowers, A Neumann, F Cerrato… - Science, 2021 - science.org
INTRODUCTION We used genomic epidemiology to investigate the introduction and spread
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …
of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the Boston area …
[HTML][HTML] Multiplexed CRISPR-based microfluidic platform for clinical testing of respiratory viruses and identification of SARS-CoV-2 variants
The coronavirus disease 2019 (COVID-19) pandemic has demonstrated a clear need for
high-throughput, multiplexed and sensitive assays for detecting severe acute respiratory …
high-throughput, multiplexed and sensitive assays for detecting severe acute respiratory …