User profiles for G. L. Wojcik

Genevieve L. Wojcik

Assistant Professor of Epidemiology, Johns Hopkins Bloomberg School of Public Health
Verified email at jhu.edu
Cited by 4256

Improving reporting standards for polygenic scores in risk prediction studies

…, P Kraft, JAL MacArthur, M Inouye, GL Wojcik - Nature, 2021 - nature.com
Polygenic risk scores (PRSs), which often aggregate results from genome-wide association
studies, can bridge the gap between initial discovery efforts and clinical applications for the …

[PDF][PDF] Human demographic history impacts genetic risk prediction across diverse populations

AR Martin, CR Gignoux, RK Walters, GL Wojcik… - The American Journal of …, 2017 - cell.com
The vast majority of genome-wide association studies (GWASs) are performed in Europeans,
and their transferability to other populations is dependent on many factors (eg, linkage …

Genetic analyses of diverse populations improves discovery for complex traits

GL Wojcik, M Graff, KK Nishimura, R Tao, J Haessler… - Nature, 2019 - nature.com
Genome-wide association studies (GWAS) have laid the foundation for investigations into the
biology of complex traits, drug development and clinical guidelines. However, the majority …

Large-scale genome-wide association study of coronary artery disease in genetically diverse populations

…, D Klarin, MG Levin, N Sinnott-Armstrong, GL Wojcik… - Nature medicine, 2022 - nature.com
We report a genome-wide association study (GWAS) of coronary artery disease (CAD)
incorporating nearly a quarter of a million cases, in which existing studies are integrated with data …

Causal effects on complex traits are similar for common variants across segments of different continental ancestries within admixed individuals

…, SS Rich, JI Rotter, HE Wheeler, GL Wojcik… - Nature …, 2023 - nature.com
Individuals of admixed ancestries (for example, African Americans) inherit a mosaic of
ancestry segments (local ancestry) originating from multiple continental ancestral populations. …

Electromechanical modeling using explicit time-domain finite elements

GL Wojcik, DK Vaughan, N Abboud… - 1993 Proceedings IEEE …, 1993 - ieeexplore.ieee.org
Piezoelectric transducers serve as electromechanical transceivers in sonar, medical
imaging, NDE, and signal processing systems. Despite their relative technical maturity, many …

Opportunities and challenges for the use of common controls in sequencing studies

GL Wojcik, J Murphy, JL Edelson, CR Gignoux… - Nature Reviews …, 2022 - nature.com
Genome-wide association studies using large-scale genome and exome sequencing data
have become increasingly valuable in identifying associations between genetic variants and …

Genome-wide association study of spontaneous resolution of hepatitis C virus infection: data from multiple cohorts

P Duggal, CL Thio, GL Wojcik, JJ Goedert… - Annals of internal …, 2013 - acpjournals.org
Chinese translation Background: Hepatitis C virus (HCV) infections occur worldwide and
either spontaneously resolve or persist and markedly increase the person's lifetime risk for …

Finite element modeling for ultrasonic transducers

NN Abboud, GL Wojcik, DK Vaughan… - Medical Imaging …, 1998 - spiedigitallibrary.org
Finite element modeling is being adopted in the design of ultrasonic transducers and imaging
arrays. Impetus is accelerated product design cycles and the need to push the technology. …

Native American gene flow into Polynesia predating Easter Island settlement

…, MC Avila-Arcos, A Sockell, JR Homburger, GL Wojcik… - Nature, 2020 - nature.com
The possibility of voyaging contact between prehistoric Polynesian and Native American
populations has long intrigued researchers. Proponents have pointed to the existence of New …