Laboratory investigation of hemoglobinopathies and thalassemias: review and update
GM Clarke, TN Higgins - Clinical chemistry, 2000 - academic.oup.com
Structural hemoglobin (Hb) variants typically are based on a point mutation in a globin gene
that produce a single amino acid substitution in a globin chain. Although most are of limited …
that produce a single amino acid substitution in a globin chain. Although most are of limited …
Relationships between developmental stability and fitness: application for conservation biology
GM Clarke - Conservation biology, 1995 - Wiley Online Library
… by Clarke and … Clarke, GM 1993h Fluctuating asymmetry of invertebrate populations as a
biological indicator of environmental quality. Environmental Pollution 82:207-211. Clarke, GM …
biological indicator of environmental quality. Environmental Pollution 82:207-211. Clarke, GM …
Data quality control in genetic case-control association studies
This protocol details the steps for data quality assessment and control that are typically carried
out during case-control association studies. The steps described involve the identification …
out during case-control association studies. The steps described involve the identification …
Basic statistical analysis in genetic case-control studies
This protocol describes how to perform basic statistical analysis in a population-based genetic
association case-control study. The steps described involve the (i) appropriate selection …
association case-control study. The steps described involve the (i) appropriate selection …
Recent human effective population size estimated from linkage disequilibrium
Effective population size (N e ) determines the amount of genetic variation, genetic drift, and
linkage disequilibrium (LD) in populations. Here, we present the first genome-wide …
linkage disequilibrium (LD) in populations. Here, we present the first genome-wide …
[BOOK][B] Genetics, demography and viability of fragmented populations.
Habitat fragmentation is one of the most ubiquitous and serious environmental threats
confronting the long-term survival of plant and animal species worldwide. As species become …
confronting the long-term survival of plant and animal species worldwide. As species become …
Fluctuating asymmetry of invertebrate populations as a biological indicator of environmental quality
GM Clarke - Environmental pollution, 1993 - Elsevier
Fluctuating asymmetry (FA) of populations of the shrimp, Palaemon elegans, and the blood
worm, Chironomus salinarius, was used to assess the environmental impact of a fertilizer …
worm, Chironomus salinarius, was used to assess the environmental impact of a fertilizer …
[HTML][HTML] Gene-lifestyle interaction and type 2 diabetes: the EPIC interact case-cohort study
…, L Arriola, A Barricarte, H Boeing, GM Clarke… - PLoS …, 2014 - journals.plos.org
In this study, Wareham and colleagues quantified the combined effects of genetic and lifestyle
factors on risk of T2D in order to inform strategies for prevention. The authors found that …
factors on risk of T2D in order to inform strategies for prevention. The authors found that …
Comparative gastrointestinal transit of pellet systems of varying density
GM Clarke, JM Newton, MB Short - International journal of pharmaceutics, 1995 - Elsevier
Model placebo multiple unit oral dosage forms were prepared by the processes of extrusion
and spheronisation. The non-invasive technique of gamma scintigraphy was used to …
and spheronisation. The non-invasive technique of gamma scintigraphy was used to …
Gastrointestinal transit of pellets of differing size and density
GM Clarke, JM Newton, MD Short - International journal of pharmaceutics, 1993 - Elsevier
The gastrointestinal transit of four multiple unit pellet dosage forms of two sizes 0.5 and 4.75
mm and two densities 1.5 and 2.6 g cm −3 was examined by gamma scintigraphy in eight …
mm and two densities 1.5 and 2.6 g cm −3 was examined by gamma scintigraphy in eight …