INTRODUCTION Brain disorders may exhibit shared symptoms and substantial epidemiological
comorbidity, inciting debate about their etiologic overlap. However, detailed study of …

Migraine is a disabling primary headache disorder that directly affects more than one billion
people worldwide. Despite its widespread prevalence, migraine remains under-diagnosed …

The present review of epidemiologic studies on migraine and headache in Europe is part of
a larger initiative by the European Brain Council to estimate the costs incurred because of …

Genes for familial hemiplegic migraine (FHM) and episodic ataxia type-2 (EA-2) have been
mapped to chromosome 19p13. We characterized a brain-specific P/Q-type Ca 2+ channel …

ContextClinical series have suggested an increased prevalence of cerebral infarction and
white matter lesions (WMLs) in migraine patients. It is not known whether these lesions are …

Objective: To describe the distribution of migraine and its subtypes in the general population.
Background: Previous population-based studies are limited by small samples or a narrow …

Migraine is a debilitating neurological disorder affecting around one in seven people worldwide,
but its molecular mechanisms remain poorly understood. There is some debate about …

Background: Migraine, particularly with aura, is a risk factor for early-onset ischemic stroke.
The underlying mechanisms are unknown, but may in part be due to migraineurs having an …

Objective: To assess health-related quality of life (HRQOL) in migraineurs in the general
population. Design: Cross-sectional study within the context of a population-based study …

Migraine is a common, heterogeneous and heritable neurological disorder. Its pathophysiology
is incompletely understood, and its genetic influences at the population level are …