We describe the landscape of somatic genomic alterations based on multidimensional and
comprehensive characterization of more than 500 glioblastoma tumors (GBMs). We identify …

We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …

Papillary thyroid carcinoma (PTC) is the most common type of thyroid cancer. Here, we
describe the genomic landscape of 496 PTCs. We observed a low frequency of somatic …

There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …

Invasive lobular carcinoma (ILC) is the second most prevalent histologic subtype of invasive
breast cancer. Here, we comprehensively profiled 817 breast tumors, including 127 ILC, …

… This network is a binary graph G = [(S,A), E], where nodes are either samples (S) or alterations
(A) … Given a partition of a graph G into distinct modules—subsets of nodes—the modularity …

… A property of this labelling is that, given two subgraphs G 1 and G 2 , cl(G 1 ) = cl(G 2 ) iff G
1 is isomorphic to G 2 . Thus, determining whether two graphs have the same canonical label …

We describe a comprehensive genomic characterization of adrenocortical carcinoma (ACC).
Using this dataset, we expand the catalogue of known ACC driver genes to include …

… with a single edge in a new global graph G. Given the observed distributions for the Jaccard
… In Step 3, MEMo attempts to extract all groups of functionally related genes from the graph G…

On the basis of multidimensional and comprehensive molecular characterization (including
DNA methalylation and copy number, RNA, and protein expression), we classified 894 renal …